Hi, You didnt mention whether u recovered from depression after taking medications or not. Leaden paralysis can be seen in melancholic depression. Also i need to know about your appetite n sleep ,weight gain to confirm melancholic depression. But one point is clear that u had depressive episode and didn't recover completely. The dose of sertaline(Daxid) should be increased to 50mg ,which is effective dose.so,first increase to 50mg and see the response in 2weeks. Even then if there is no response,then we can change the medication. Once u start the treatment for depression, u should continue for atleast 6-9months depending on response