I am 74 i always suffer from HBP but with medication it's ok I am taking nebilet 5mg at 9.00am and micardis 80mg at 3.00pm and the BP was ok 150/70 or 146/66 heart rate avarge 51 to 56 but what happen when rammadn came and I fast it raised to 190/80 in the 1.00pm so I start taking hydralazini 25mg at 12 midnight and micardis 80mg at 7.00pm and neblit 5mg at 3.25 am what happen that suddenly both stop working effectively I was only taking 2 medicine at the morning and after noon and till the next day the reading is fine so why the don't last as before