Usually after the age of 45 the hormones decrease making it difficult to conceive. But that doesn't mean that u won't conceive. U will have to start by monitoring ur cycle by usg to see whether u ovulate naturally. If u don't then u might require treatment. Treatment starts by taking oral medications. Along with that u need to check for ur tubal patency and a husband's semen report to check exactly who has a problem. On the above basis it can be easily figured out do that u can conceive.