Interindividual variation are a lot but fluoxetine works for many. OCD is a complex illness, it is not so simple to break it down to fluoxetine. Every illness has social and psychological factors which has a impact on how medicine works.

The best evidence base for OCD are tricycles like clomipramine followed by SSRI’s like paroxetine, fluvoxamine and fluoxetine. Evidence to support efficacy of sertraline and escitalopram is weaker. Generally higher doses are warranted for longer durations in OCD.

Yes most of the studies have been done with Fluuoxetine and it is better for OCD in general.

Hi there, A detailed medical and psychiatric history is always needed for every case. Your question is related to the drug Fluoxetine for OCD . From time to time , the medications may change. Before Fluoxetine, other drug like Cloimipramine was being written.There are other drugs also available.But remember, every drug has its own advantages and side effects profiles. Well Fluoxetine is also good but the dosage depend on the severity of the symptoms too. And the side effects profile will differ.