Both contain the same ingredient, but Oleanz RT can be dissolved in liquids or mixed in solid foods as powder. This helps in giving it to patients who are unable or unwilling to take oral tablets in a routine manner.

Oleanz and Oleanz Rapitab both contain Olanzapine. The difference is the formula of the actual tablet. Oleanz Rapitab is orally disintegrating, that is it starts dissolving and getting absorbed as soon as the patient puts it in the mouth. If the patient has difficulty swallowing, or is known to just keep the tablet in mouth and not swallow, Oleanz Rapitab is better as it starts to dissolve in mouth itself.

Second one is dispersable and better to give as it can be mixed with food,less chances of cheeking too