hello There's no known cure for ichthyosis, so the goal of treatment is to manage the condition. Medications Treatments may include: Alpha hydroxy acids, such as lactic acid and glycolic acid. Treatment can include prescription creams and ointments that contain acids that help control scaling and increase skin moisture. Retinoids. Your doctor may prescribe these vitamin A-derived medications in severe cases. They reduce the production of skin cells. Side effects from the medication may include eye and lip inflammation, bone spurs and hair loss. for further queries contact dermatologist.