Hello, The total IgE test may be used to screen for and detect allergic diseases. Variations in the upper limit of normal total serum IgE have been reported: they can range from 150 to 1,000 UI/ml; but the usually accepted upper limit is between 150 and 300 UI/ml. Elevated IgE levels says chronic allergic condition or parasitic infestation, non atopic allergy. He may need to take medications for life time .