You think that some nano particles have entered your brain through your palms and through your body when you touched the mouse. Now, you feel sensations in your right hand palms and your brain.
It is difficult to suggest anything with such little history but from what symptoms you have described it seems that you are experiencing 'delusional parasitosis'. This condition is treatable, I would advise you to consult a psychiatrist for a detailed evaluation and a treatment plan.
Next Steps
Consult a psychiatrist as early as possible.