Your mother, if she is 50 years old, needs a gynaecologist consultation. Have a ultrasound scan done of the abdomen and pelvis. Some blood tests to study her hormones.
Mood swings, personality changes in this age for women can be related to their hormones. If that is ruled out then a change in environment and more supportive interactions could help. A psychologist consult for her and the family will always be helpful.
Next Steps
Gynaecologist consultation and ultrasound scan with blood tests as advised