Greetings. Please take note of the following: 1. No creams or oral medicines will really make any significant difference in the shape of your nose. 2. You'll need to see a qualified dermatologist - if u want to modify the shape - in case of injection of filler substances into the nose 3. If you want to reduce volume or change the shape significantly and permanently - then pls see a plastic surgeon for a rhinoplasty operation . Hope this helps. Warm regards. Dr Govind Suresh Mittal, Bengaluru