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Mouth sores as side effects of Veenat
Summary as follows
Diagnosed with CML chronic phase in feb 2018
Started Veenat 400 On March 6 th.
WBC counts were under control stable at appx 5000
BCR ABL at 6 months was 0.953 %
Developed mouth soars in July 2018
Tried all types remedies but does not subside
Need advise as follows
Option 1. Stop veenat for a week and restart hopefully it subsides
Option. 2. Switch to 2 Nd generation drug
Option 3 . Switch to 2nd generation drug for a limited period and come back to generation 1 Rather than giving a break
Main concern. Is it right to stop & give a break to the drug. Will it effect long term goals as well as 1 yr achievement of deep molecular remission
You had very good response to imatinib. In July you had mouth ulcer now what is the situation. Still you had. It is not very good decision to stop imatinib until you had severe toxicities. And imatinib is not a drug to produce that severe mouth sore.in presence of very good response to imatinib change into 2 nd generation is not ideal. My advice to continue imatinb
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