With the administration of clomiphene, an antiestrogen,
approximately 50% of patients achieve partial reduction in breast size,
and approximately 20% of patients note complete resolution. Adverse
effects, while rare, include visual problems, rash, and nausea.
Tamoxifen, an estrogen antagonist, is effective for recent-onset and
tender gynecomastia. Up to 80% of patients report partial to
complete resolution. Nausea and epigastric discomfort are the main
adverse effects.
Other drugs used, albeit less frequently, include danazol. Danazol,
a synthetic derivative of
testosterone, inhibits pituitary secretion of
LH and follicle-stimulating hormone (
FSH), which decreases estrogen
synthesis from the testicles...consult plastic surgeon they will help you