First of all glutathione injections itself are not FDA approved. But when it is given systemically there are various methods employed, some prefer giving it intravenously as a push directly or some prefer to mix it with dextrose in 100ml pint or it is even give as an intramuscular injection. All three methods are more about the personal preference of the physician. But as per the company recommendations giving it with the dextrose great is what is preferred and this is the same method that I use. Hope this is helpful;.