Hi. Greetings. To the best of my knowledge there are no defined studies on success of carboxy therapy for dark circles.. Same with other therapies also. However it's important to know the cause. For hereditary dark circles you can try the therapy you mentioned / Prp therapy/ rerinol creams and sunscreen however, you'll need some form of long term maintenance to prevent recurrence of dark circles. Further queries may be sent on follow up private chat. Dr Govind Suresh Mittal.