Patient was admitted with bilateral pleural effusion at Ruby Hospital Kolkata. Doctor tapped the water and test of the water found No M cell and but CT scan of abdomen and chest showed lots of Lymph node. Later after biopsy the detected that the disease is AITL one of the category of NHL, which is very aggressive in nature. They have gone for bone marrow and predicting the stage is 4 or 3B and started with CHOP21 treatment.