Hi greetings - i hope you are on these multiple medications - on prescription of a certified and qualified PSYCHIATRIST - AND PLEASE MAKE SURE THAT THE ISOTRETINOIN OR SOTRET HAS BEEN ADVISED BY A QUALIFIED DERMATOLOGIST. Isotretinoin does not have any interaction with any of the medication above - but be under weekly follow up with your dermatologist/psychiatrist if u are on sotret since we usually avoid in in individuals with depression (unless acne itself is the cause of depression) - please discuss this with your dermatologist. Further queries may be sent on follow up messaging - Dr Govind Suresh Mittal, Bangalore