Typhidot Antibodies

Typhidot antibodies ELISA blood test is used to detect the presence of antibodies to S.typhi in the blood.

What is Typhoid fever?

The organism which causes typhoid is called Salmonella typhi and the organisms that cause paratyphoid can be Salmonella paratyphi A or Salmonella paratyphi B or Salmonella paratyphi C. Typhoid fever is a bacterial infection caused by Salmonella typhi and grows in the intestine and blood. During infection, patients body produce antibodies against Salmonella typhi O and H. They are spread by eating contaminated food or drinking contaminated water. The symptoms include high fever, vomiting, diarrhea, and gastrointestinal problems. Some people may have the infection without exhibiting any symptoms and are able to transmit the organism.

Paratyphoid fever is caused by any of the above-mentioned organisms. These organisms usually grow in intestines and blood. They are spread by eating contaminated food or drinking contaminated water. The symptoms of this fever include high fever, weakness, poor appetite, headache, and in rare conditions skin rash may be developed with pink colored spots, etc. Usually, the symptoms are experienced after 6-30 days after the exposure to the organism. In some rare conditions, individuals with the organism may not get affected and are able to spread it to others. Typhoid and paratyphoid fevers are generally group termed as Enteric fever.

Why this test is recommended?

This test is performed to check the presence of Salmonella species antibodies in the blood. It also helps to diagnose typhoid fever caused by microorganisms like Salmonella typhi, Salmonella paratyphi A, B, C. The doctor may ask you to undergo this test if you are suffering from symptoms like fever, weakness, headache, loss of appetite, pink colored spots, pain in abdomen, chills, nausea or vomiting, constipation, muscle weakness, skin rash, etc. If an individual is on the treatment for typhoid and paratyphoid fever and using medications like ciprofloxacin, azithromycin, ceftriaxone, then the doctor may ask to perform this test to evaluate and to check the effectiveness of the treatment.

How often this test is performed?

If you have been diagnosed with typhoid or paratyphoid fever, your doctor may advise you to get this test done once in every 2 weeks based on your clinical condition.

The normal reference range may be different depending on gender, age, health conditions, and other factors.

If your test results are positive it may indicate the presence of infection in the body. The presence of infection in the blood may indicate that you have typhoid or paratyphoid.

If your test results are negative, it may indicate the absence of the infection in the body.

If you get abnormal test results, consult your doctor immediately. Your doctor may recommend other tests depending on your test results.