High resolution chromosome analysis is the method of choice in neonates for detecting numerical and structural chromosome aberrations. This assay not only detects extra chromosomes, such as chromosome 21 in Down syndrome, but it also identifies structural chromosome changes, including subtle deletions and additions not identified by conventional Karyotyping techniques. High resolution allows a more detailed analysis of chromosome structure, which enables detection of more subtle chromosome abnormalities. High-resolution chromosome analysis is suggested for patients who have a family history of a particular abnormality and for patients who have very specific clinical features.
Also known as: Chromosome Analysis High Resolution.