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Double Marker

What is this test?

Double marker test is a specific blood test performed in pregnant women to detect any chromosomal malformations in the fetus. This test is usually recommended for women above 35 years of age because they are at a high risk of giving birth to a baby with chromosomal abnormalities. However, even younger women who are less than 35 years of age are also asked to undergo this test during pregnancy.

Why this test is performed?

The double marker test is a proven test for detecting any abnormalities or any issues present. This test finds out the abnormalities in the chromosomes of the fetus. The abnormalities in the chromosomes may lead to serious conditions like the growth of the baby may be affected. With the help of this test disorders such as Edwards syndrome, Down’s syndrome can be detected. Edward’s syndrome is a condition which leads to severe developmental delays due to chromosome 18 abnormality. Down’s syndrome is the delay of growth, development, and intelligence due to chromosome 21 disorder. This test is usually conducted after 8 weeks to 14 weeks of pregnancy. This test is generally recommended in women above 35 years of age or in women with a family history of birth defects or if first child has birth defects or has a history of Type-1 diabetes (insulin dependent).

Test Preparation

Inform your doctor if you are on any medications, have any allergies or underlying medical conditions before your Double Marker. Your doctor will give specific instructions depending on your condition on how to prepare for Double Marker.

No specific preparation is required for this double marker test.

Understanding your test results

The double marker test results are usually given as screen positive and screen negative.

If your test results show screen positive, it may indicate that you are at the high risk and there are chances of having chromosomal abnormalities in the fetus.

If your test results show screen negative, it may indicate that there is a low risk of chromosomal abnormalities.

GenderAge groupsValue
FEMALEAll age groups25700-288000 mIU/ml
FEMALEAll age groups1 MoM (multiple of median)
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