CD99 is the product of the MIC2 gene. It is expressed in normal tissues including some lymphocytes, pancreatic islet cells, granulosa cells of the ovary, Sertoli cells of the testis, and ependymal cells of the central nervous system. It is strongly expressed in Ewing sarcoma/primitive neuroectodermal tumor, distinguishing it from other small round blue cell tumors of childhood and adolescence. CD99 is a glycosylated transmembrane protein encoded by the MIC2 gene, highly expressed in all Ewing's sarcomas (EWS). CD99 has been involved in many physiological processes, such as cell adhesion, apoptosis and differentiation and intracellular trafficking.
No special preparation is needed for CD 99. Inform your doctor if you are on any medications or have any underlying medical conditions or allergies before undergoing CD 99. Your doctor depending on your condition will give specific instructions.
|UNISEX||All age groups||Test is positive if the conditions listed are detected|