CD14 is a glycosylphosphatidylinositol (GPI)-linked glycoprotein that is preferentially expressed by mature cells of monocytic lineage (monocytes, macrophages, Langerhans cells) and on follicular dendritic cells. Lower levels of expression are observed on neutrophils. CD14 is important for the recognition and clearance of bacterial lipopolysaccharides and apoptotic cells. This immunostain may be useful as a marker of histiocytic and monocytic lineage in acute leukemias.
No special preparation is needed for CD 14. Inform your doctor if you are on any medications or have any underlying medical conditions or allergies before undergoing CD 14. Your doctor depending on your condition will give specific instructions.
|UNISEX||All age groups||Test is positive if the conditions listed are detected|