Autoimmune liver disease (eg, autoimmune hepatitis and primary biliary cirrhosis) is characterized by the presence of autoantibodies including smooth muscle antibodies (SMA), antimitochondrial antibodies (AMA), and anti-liver/kidney microsomal antibodies type 1 (anti-LKM-1).(1) Subtypes of autoimmune hepatitis (AIH) are based on autoantibody reactivity patterns. Anti-LKM-1 antibodies serve as a serologic marker for AIH type 2 and typically occur in the absence of SMA and antinuclear antibodies. These antibodies react with a short linear sequence of the recombinant antigen cytochrome monooxygenase P450 2D6.(2) Patients with AIH type 2 more often tend to be young, female, and have severe disease that responds well to immunosuppressive therapy.
No special preparation is needed for Anti Lkm 1 Antibodies Qualitative Immunoassay / Elisa Blood Serum. Inform your doctor if you are on any medications or have any underlying medical conditions or allergies before undergoing Anti Lkm 1 Antibodies Qualitative Immunoassay / Elisa Blood Serum. Your doctor depending on your condition will give specific instructions.
Gender | Age groups | Value |
UNISEX | All age groups | Negative |