Annexin-1 is a molecule specific to hairy cell leukemia that can be used to differentiate this disease from other B-cell lymphomas. Annexin-1 (A1) was identified by gene expression profiling studies of hairy cell leukemia. In the appropriate context, positivity for annexin A1 favors a diagnosis of hairy cell leukemia. Normal granulocytes and precursors also express annexin A1, serving as a positive internal control in bone marrow specimens.
No special preparation is needed for Annexin 1 Immunohistochemistry Biopsy Tissue. Inform your doctor if you are on any medications or have any underlying medical conditions or allergies before undergoing Annexin 1 Immunohistochemistry Biopsy Tissue. Your doctor depending on your condition will give specific instructions.
Gender | Age groups | Value |
UNISEX | All age groups | The result is positive in case of detection of Hairy Cell Leukemia |