Adenovirus Antibodies Cft Igg Immunoflorescence Blood

Adenoviruses, medium-sized (90-100 nm), non-enveloped icosohedral viruses with double-stranded DNA, have over 50 immunologically distinct types that cause infections in humans. Adenoviruses usually cause respiratory illness with symptoms ranging from the common cold to pneumonia, croup, and bronchitis. Adenoviruses can cause other illnesses such as gastroenteritis, conjunctivitis, cystitis, and less commonly, neurological disease. Infants and individuals with weakened immune systems are at high risk for severe complications of adenovirus infection and adenoviruses commonly cause acute respiratory illness in military recruits. Some asymptomatic people infected with adenoviruses have ongoing infections in their tonsils, adenoids, and intestines and can shed the virus for months or years. The virus can persist outside the body for long periods. Adenovirus infections can be detected using antigen detection, polymerase chain reaction assay, virus isolation, and serology. Typing is usually done by hemagglutination-inhibition and/or neutralization with type-specific antisera or by molecular methods.