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Zyrof 3 K Injection
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Zyrof 3 K Injection

Manufactured byZydus Cadila
ContainsRofecoxib
Description
Zyrof 3 K Injection belongs to the Nonsteroidal anti-inflammatory drug group. This medicine is used for relieving pain, swelling, and inflammation associated with medical conditions such as rheumatoid arthritis, osteoarthritis, gout, ankylosing spondylitis, etc. It is banned for sale in India.
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Side effectsConcernsUsageRelated products

Side effects

Major & minor side effects for Zyrof 3 K Injection

  • Headache
  • Nausea or Vomiting
  • Swelling of face, lips, eyelids, tongue, hands and feet
  • Severe stomach ache
  • Blurred vision
  • Hives and wheezing
  • Pain at the injection site

Uses of Zyrof 3 K Injection

What is it prescribed for?

  • Musculoskeletal pain and inflammation
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for this medicine to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to rofecoxib, or any other inactive ingredient present along with the formulation.

Peptic Ulcer

This medicine is not recommended for use in patients with peptic ulcer disease due to the increased risk of worsening of the patient's condition.

Heart diseases

This medicine is not recommended for use in patients having a history of heart conditions. The risk of fatal adverse effects are even higher if you have an active condition like heart block, rhythm disorder etc.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.
General warnings

Heart diseases

This medicine should be used with caution in patients with heart diseases due to the increased risk of adverse effects on the heart, especially after prolonged use. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Gastrointestinal ulcers or bleeding

This medicine is not recommended for use in patients with a history of gastrointestinal ulcers and bleeding since it may worsen the patient's condition. Replacement with a suitable alternative should be considered under your doctor's supervision.

Other medicines

This medicine is known to interact with a large number of other medications that you might possibly be taking. Report the use of all medications including supplements and herbs to the doctor. Do not stop the use of any medicine without consulting your doctor.

Kidney diseases

This medicine should be used with caution in patients with kidney diseases due to the increased risk of worsening of the patient's condition. Regular monitoring of kidney function tests is necessary for such patients while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be necessary in some cases based on the clinical condition.

Missed Dose

Since this medicine is usually administered by a qualified healthcare professional in the clinical/hospital setting, the likelihood of a missed dose is very low.

Overdose

Since this medicine is administered in the hospital setting by a qualified healthcare professional, the likelihood of an overdose is very less. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Lithium

Ramipril

Warfarin

Adefovir

Amikacin

Cidofovir

Clopidogrel

Aspirin

Disease interactions

Heart Disease

This medicine may cause a heart attack, stroke, or other associated symptoms after prolonged use. This risk is especially higher in patients with a history of heart diseases. Close monitoring of heart function is recommended for such patients. Report any symptoms such as chest pain, shallow breathing, speech slurring, weakness, etc. to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Liver Disease

This medicine should be used with extreme caution in patients with liver function impairment or active liver diseases due to the increased risk of worsening of the patient's condition. Close monitoring of liver function is necessary while receiving this medicine. Report any incidences of nausea, fever, rashes, dark-colored urine, etc. to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Gastrointestinal Diseases

This medicine should be used with caution in patients with any disease of the stomach or intestine. The risk of worsening of symptoms is very high while using this medicine. Report any unusual signs and symptoms to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
This medicine is usually administered in the clinical/hospital setting under the supervision of a qualified healthcare professional. Follow all the instructions given by your doctor. Inform the doctor if you have a known allergy to this medicine. Report all your current medicines as well as your medical conditions to the doctor before receiving this medicine.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine works by reducing the formation of certain substances in the body that causes pain and swelling.
Legal Status

Banned

Unknown

Unknown

Unknown

Classification

Category

Nonsteroidal anti-inflammatory agents

Schedule

Schedule H

Rofecoxib | C17H14O4S - PubChem [Internet]. Pubchem.ncbi.nlm.nih.gov. 2017 [cited 21 March 2017]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/5090

Rofecoxib - DrugBank [Internet]. Drugbank.ca. 2020 [cited 3 February 2020]. Available from:

https://www.drugbank.ca/drugs/DB00533
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Information on this page was last updated on 14 Feb 2020

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.