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Zoshan (50/150 mg) Tablet
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Zoshan (50/150 mg) Tablet

Manufactured byBion Therapeutics (India) Pvt. Ltd.
ContainsDiclofenac (50 mg) + Tolperisone (150 mg)
Description
Zoshan (50/150 mg) Tablet is a combination medicine that consists of diclofenac and tolperisone. It is used for the treatment of acute muscle spasms in adults. It provides relief from swelling, stiffness and pain associated with muscle spasms and arthritis. It improves muscle tone by improving blood flow to the muscles and blocks certain chemicals that signal pain thus, it reduces stiffness and provides relief from pain. Zoshan (50/150 mg) Tablet may cause some side effects like drowsiness, heartburn, loss of appetite, vomiting, nausea, stomach pain and diarrhoea. It may affect your ability to drive as it can cause drowsiness and blurred vision. Inform your doctor if any of these side effects persist or get worse. Do not take this medicine if you are allergic to it. Zoshan (50/150 mg) Tablet should be taken with food to reduce the chances of stomach upset. Inform your doctor if have ulcers, bleeding issues, liver or kidney problems while prescribing this medicine to you. It may not be recommended for use if you have asthma that is affected by NSAIDs (Non-steroidal anti-inflammatory drugs) like aspirin. Do not consume alcohol while taking this medicine as it can cause damage to the stomach. Consult your doctor before taking Zoshan (50/150 mg) Tablet if you are pregnant or if you are breastfeeding.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Zoshan (50/150 mg) Tablet

  • Abdominal pain
  • Diarrhea
  • Nausea and Vomiting
  • Skin Rash
  • Dry mouth
  • Muscle weakness
  • Breathlessness
  • Low blood pressure
  • Swelling of eyes and lips
  • Abdominal discomfort
  • Indigestion
  • Dizziness
  • Increased heartrate

Uses of Zoshan (50/150 mg) Tablet

What is it prescribed for?

  • Muscle spasm
  • Ankylosing spondylitis
  • Osteoarthritis
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    Zoshan (50/150 mg) Tablet starts showing its effects within 30 minutes after taking it.
  • How long do the effects of this medicine last?
    The amount of time for which Zoshan (50/150 mg) Tablet remains active in the body is not known.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during the treatment with Zoshan (50/150 mg) Tablet due to the increased risk of serious side effects such as gastrointestinal bleeding, dizziness, fatigue and weakness.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported for Zoshan (50/150 mg) Tablet.
  • Can this medicine be taken during pregnancy?
    Zoshan (50/150 mg) Tablet is not recommended to be used in pregnancy as not enough information is available regarding its safety. Consult your doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    Zoshan (50/150 mg) Tablet is not recommended for use during breastfeeding unless absolutely necessary. Consult your doctor before taking this medicine. If the medicine is used, the infant should be observed for any undesirable effects.

Allergy

Avoid taking Zoshan (50/150 mg) Tablet if you are allergic to diclofenac, other NSAIDs, tolperisone, or any other inactive ingredient present along with them. Seek medical attention if you come across any allergic reactions such as a skin rash, hives (itchy, painful eruptions that sting), swelling (face, lips, tongue, etc.), breathing difficulty, etc.

Myasthenia gravis

Zoshan (50/150 mg) Tablet is not recommended for use if you have myasthenia gravis (a neuromuscular disorder that causes weakness in your skeletal muscles, which are the muscles your body uses for movement) due to the increased risk of worsening your condition.

Peptic ulcer

Peptic ulcers are the sores in the lining of the stomach and intestine. Zoshan (50/150 mg) Tablet is not recommended for use if you have peptic ulcer disease, as it may cause stomach bleeding and worsen your condition.

Severe kidney disease

Zoshan (50/150 mg) Tablet is not recommended if you have severe kidney disease as this medicine may cause serious undesirable effects and may worsen your condition.

Severe heart failure

Heart failure is a chronic, progressive condition in which the heart muscle is unable to pump enough blood to meet your body's needs for blood and oxygen. Zoshan (50/150 mg) Tablet is not recommended for use if you are a patient with heart failure due to the increased risk of worsening your condition.

NSAID-induced asthma

Non-steroidal anti-inflammatory drugs (NSAIDs)-induced asthma is an allergic condition of the respiratory system that may occur when you used NSAIDs in higher doses or for a long time. These medicines narrow the airway and provoke mucous secretion in the airway, causing severe breathing difficulty. Zoshan (50/150 mg) Tablet is not recommended for use if you have this condition.

Coronary artery bypass surgery (CABG)

Coronary artery bypass graft (CABG) is a surgical procedure that diverts the blood from narrowed or blocked vessels in the heart to improve its blood supply. Zoshan (50/150 mg) Tablet is not recommended for use before, during, or after a coronary artery bypass graft surgery as it may cause heart failure.
Warnings for special population

Pregnancy

Zoshan (50/150 mg) Tablet is not recommended to be used in pregnancy as not enough information is available regarding its safety. Consult your doctor before taking this medicine.

Breast-feeding

Zoshan (50/150 mg) Tablet is not recommended for use during breastfeeding unless absolutely necessary. Consult your doctor before taking this medicine. If the medicine is used, the infant should be observed for any undesirable effects.
General warnings

Heart attack and stroke

Zoshan (50/150 mg) Tablet should be used with caution if you have pre-existing heart disease due to the increased risk of heart attack and stroke. Your doctor may adjust the dose of this medicine or may suggest a suitable alternative if required based on your condition.

Coronary artery bypass surgery

Zoshan (50/150 mg) Tablet should not be taken to relieve muscle spasms before, during, or after a coronary artery bypass graft surgery due to the increased risk of severe side reactions.

Gastro-intestinal bleeding

Zoshan (50/150 mg) Tablet may cause severe gastrointestinal bleeding and perforation after prolonged usage. These effects may occur with or without warning symptoms. This risk is especially higher in old people and in people with a history of gastrointestinal diseases. Hence, if you experience any unusual symptoms while using this medicine, report to your doctor immediately.

Dizziness

Zoshan (50/150 mg) Tablet may make you feel sleepy or dizzy. Hence, do not perform any activities that require high mental alertness like driving a vehicle or operating a heavy machine if you experience these symptoms after taking this medicine.

Liver disease

Zoshan (50/150 mg) Tablet should be used with caution if you have liver problems due to the increased risk of severe side effects. Your doctor may monitor your liver function as needed while you are on treatment with this medicine.

Skin rash

Zoshan (50/150 mg) Tablet may cause serious skin allergies. Symptoms such as rashes, hives, fever, or other allergic symptoms should be reported to the doctor promptly.

Missed Dose

Take the missed dose of Zoshan (50/150 mg) Tablet as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

Never take more than the prescribed dose. Seek emergency medical treatment if you have taken an overdose of Zoshan (50/150 mg) Tablet.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during the treatment with Zoshan (50/150 mg) Tablet due to the increased risk of serious side effects such as gastrointestinal bleeding, dizziness, fatigue and weakness.
Interaction with Medicine

Allopurinol

Methotrexate

Ramipril

Adefovir

Apixaban

Ketorolac

Probenecid

Methocarbamol

Tetracyclines

Disease interactions

Asthma

Zoshan (50/150 mg) Tablet is not recommended for use if you have a known history of NSAID-induced asthma. Your doctor may adjust the dose of this medicine or may suggest a suitable alternative if required based on your condition.

Fluid retention

Zoshan (50/150 mg) Tablet may cause oedema (swelling caused by the accumulation of fluid in a part of the body) if you have a problem of fluid retention. Your doctor may closely monitor your blood pressure, electrolyte levels, and heart function based on your clinical condition. Your doctor may adjust the dose of this medicine or may suggest a suitable alternative if required based on your condition.

Gastro-intestinal toxicity

Zoshan (50/150 mg) Tablet may cause damage to the stomach, intestines or liver if you have gastrointestinal problems. Report any symptoms such as chronic indigestion, blood in stool or vomit, etc., to your doctor immediately. Your doctor may adjust the dose of this medicine or may suggest a suitable alternative if required based on your condition.

Heart diseases

Zoshan (50/150 mg) Tablet may cause a heart attack or stroke if you have pre-existing heart disease. Your doctor may monitor your heart function as needed while you are on treatment with this medicine. Report any symptoms such as chest pain, shallow breathing, speech slurring and/or weakness to the doctor immediately. Your doctor may adjust the dose of this medicine or may suggest a suitable alternative if required based on your condition.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take Zoshan (50/150 mg) Tablet as directed by the doctor. It can be taken with food to avoid stomach upset. Drink plenty of water to prevent the formation of kidney stones. Do not take more or fewer doses than advised/prescribed. Consult the doctor if you experience any undesirable effects. Do not stop using this medicine without consulting your doctor. Avoid consuming alcohol while using Zoshan (50/150 mg) Tablet as it may cause gastrointestinal problems and may make you feel drowsy. Keep the medicine away from the reach of children and pets. Ensure that the unused medicine is disposed of properly.
Miscelleneous

To be taken with food

To be taken as instructed by doctor

May cause sleepiness

How it works
Diclofenac works by blocking the action of certain substances in the body that cause pain and swelling. Tolperisone relaxes your muscles and improves blood flow to the muscles. Together they provide relief from the pain and decrease muscle contraction and stiffness.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Muscle relaxants, Nonsteroidal anti-inflammatory agents, Analgesics

Schedule

Schedule H

Drugs, H., 2021. Diclofenac: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 15 September 2021].

https://medlineplus.gov/druginfo/meds/a689002.html>

Beximcopharma.com. 2021. Beximco Pharmaceuticals Ltd.. [online] Available at: < [Accessed 14 September 2021].

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Ogyei.gov.hu. 2021. [online] Available at: < [Accessed 14 September 2021].

https://www.ogyei.gov.hu/kiseroirat/ph/ph_0000048451.pdf>

Pubchem.ncbi.nlm.nih.gov. 2021. Tolperisone. [online] Available at: < [Accessed 14 September 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Tolperisone>

Inceptapharma.com. 2021. Incepta Pharmaceuticals | A leading pharmaceutical company in Bangladesh. [online] Available at: < [Accessed 15 September 2021].

http://www.inceptapharma.com/view-product.php?pid=82>

Accessdata.fda.gov. 2021. [online] Available at: < [Accessed 15 September 2021].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/019201s039s040lbl.pdf>

Medicines.org.uk. 2021. Diclofenac Sodium 50mg Gastro-Resistant Tablets - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 7 September 2021].

https://www.medicines.org.uk/emc/product/2660/smpc#UNDESIRABLE_EFFECTS>

Medsafe.govt.nz. 2021. [online] Available at: < [Accessed 7 September 2021].

https://www.medsafe.govt.nz/Consumers/cmi/d/diclofenacsandoz.pdf>
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Information on this page was last updated on 17 Sep 2021

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