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Urief 4 mg Tablet
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Urief 4 mg Tablet

Manufactured byEisai Pharmaceuticals India Ltd.
ContainsSilodosin
Description
Urief 4 mg Tablet is an antiadrenergic medicine, which is used to treat the signs and symptoms of benign prostatic hyperplasia (prostate enlargement). This medicine is not recommended for use in patients suffering from severe kidney function or liver function impairment and patients less than 18 years of age.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Urief 4 mg Tablet

  • Chills
  • Dizziness
  • Confusion
  • Headache
  • Diarrhea
  • Nasal congestion

Uses of Urief 4 mg Tablet

What is it prescribed for?

  • Benign prostatic hyperplasia
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for this medicine to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of severe adverse effects. These side effects may include dizziness, headache, lightheadedness, etc. It is advised that you do not perform activities such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women.

Allergy

This medicine is not recommended for use in patients with a known allergy to silodosin or any other inactive ingredients present in the formulation.

Severe Kidney disease

This medicine is not recommended for use in patients with a known history of severe kidney function impairment due to the increased risk of worsening of the patient's condition.

Severe liver disease

This medicine is not recommended for use in patients with a known history of severe liver function impairment due to the increased risk of worsening of the patient's condition.

Strong CYP3A4 inhibitors

This medicine is not recommended for use in patients receiving therapy with CYP3A4 inhibitors due to the increased risk of serious adverse effects.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women.

Breast-feeding

This medicine is not recommended for use in breastfeeding women.
General warnings

Elderly patients

This medicine should be used with caution in elderly patients due to the increased risk of very low blood pressure. Regular monitoring of blood pressure levels is necessary for these patients. Report any unusual symptoms such as dizziness, lightheadedness, headache, etc. to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Cataract surgery

This medicine may increase the risk of intraoperative floppy iris syndrome. Patients undergoing cataract surgery should inform the surgeon about the current or previous use of this medicine, so that the surgeon can make appropriate changes in the surgical technique to reduce the risk of intraoperative floppy iris syndrome.

Driving or operating machinery

This medicine may cause blurred vision, dizziness, or drowsiness in some patients. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Effect on women

This medicine is not recommended for use in women. Since this medicine may be absorbed through the skin, it is recommended that you wash the area that comes in contact with this medicine immediately with soap and water.

Use in children

This medicine is not recommended for use in patients less than 18 years of age since the safety and efficacy of use are not clinically established.

Missed Dose

Take the missed dose as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of severe adverse effects. These side effects may include dizziness, headache, lightheadedness, etc. It is advised that you do not perform activities such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
Interaction with Medicine

Amitriptyline

Alprazolam

Nefazodone

Clotrimazole

Baclofen

Chlordiazepoxide

Canagliflozin

Conivaptan

Disease interactions

Kidney Disease

This medicine should be used with extreme caution in patients with mild to moderate kidney function impairment due to the increased risk of worsening of the patient's condition. Close monitoring of kidney function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Liver Disease

This medicine should be used with extreme caution in patients suffering from liver function impairment due to the increased risk of worsening of the patient's condition. Close monitoring of liver function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take this medicine as instructed by your doctor. Do not take in larger amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

To be taken with food

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine works by relaxing the muscles of the bladder and the prostate.
Legal Status

Approved

Unknown

Approved

Unknown

Classification

Category

Antiadrenergic agents, peripherally acting

Schedule

Schedule H

Silodosin - DrugBank [Internet]. Drugbank.ca. 2020 [cited 19 June 2020]. Available from:

https://www.drugbank.ca/drugs/DB06207

Silodosin: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2020 [cited 19 June 2020]. Available from:

https://medlineplus.gov/druginfo/meds/a609002.html

Silodosin [Internet]. Pubchem.ncbi.nlm.nih.gov. 2020 [cited 22 June 2020]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/Silodosin
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Information on this page was last updated on 1 Jul 2020

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