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Troypipera-T 4.5 Injection

Manufactured byTROIKAA PHARMACEUTICALS LTD
ContainsPiperacillin (4000 mg) + Tazobactam (500 mg)
Description
Troypipera-T 4.5 Injection is a combination of Piperacillin and Tazobactam. It is used for the treatment of bacterial infections that affect the lungs, urinary tract, skin, etc. This medication is effective only for the treatment of infections caused by bacteria and not viruses. Troypipera-T 4.5 Injection is effective against a large number of bacteria. Piperacillin works by preventing the formation of bacterial cell walls and killing the infection-causing bacteria. Tazobactam protects Piperacillin and ensures extended anti-bacterial activity. Troypipera-T 4.5 Injection may cause some common side effects such as diarrhoea, upset stomach, headache, sleeplessness, skin rash and itching, etc. Consult your doctor if these symptoms persist or if they become severe. Troypipera-T 4.5 Injection is given by your doctor in a clinic or a hospital setting. The dose and duration of the treatment will depend on your condition. Follow the instructions given by your doctor and continue receiving the medicine for the prescribed duration. Not completing the full course of therapy may result in decreased effectiveness of the medicine or an increased risk of re-infection that would be difficult to treat in the future. Troypipera-T 4.5 Injection is not recommended if you are allergic to it. This medicine is not advisable for children below 2 years of age. Inform your doctor if you have any kidney/liver problems or a history of seizures (fits) before starting treatment with this medicine. Consult your doctor if you are pregnant or are breastfeeding.

Side effects

Major & minor side effects for Troypipera-T 4.5 Injection

  • Diarrhoea
  • Headache
  • Sleeplessness
  • Abdominal pain
  • Nausea and Vomiting
  • Stomach upset
  • Skin rash and itching
  • Fever
  • Injection site reactions (redness, pain, swelling)
  • Joint and muscle pain

Uses of Troypipera-T 4.5 Injection

What is it prescribed for?

  • Community acquired pneumonia
  • Nosocomial Pneumonia or Hospital-acquired Pneumonia (HAP)
  • Urinary Tract Infection
  • Intra abdominal infection
  • Skin and Skin Structure Infection
  • Bacterial Septicaemia
  • Neutropenia
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The time required for Troypipera-T 4.5 Injection to show its action is not clinically known.
  • How long do the effects of this medicine last?
    The effect of Troypipera-T 4.5 Injection lasts for an approximate duration of 4-7 hours after taking it.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendencies have been reported with Troypipera-T 4.5 Injection.
  • Can this medicine be taken during pregnancy?
    Due to a lack of safety and efficacy studies in pregnant women, the risk to your developing foetus is not known. If you are pregnant, take Troypipera-T 4.5 Injection only if prescribed by your doctor.
  • Can this medicine be taken while breast-feeding?
    Troypipera-T 4.5 Injection passes into breast milk in very low quantities and may cause diarrhoea in your breastfed infant. If you are breastfeeding, consult your doctor.

Allergy

Avoid taking Troypipera-T 4.5 Injection if you are allergic to it. Seek immediate medical attention if you notice any symptoms of allergic reactions such as skin rash, itching/swelling (especially of your face/tongue/throat), severe dizziness, breathing difficulty, etc.
Warnings for special population

Pregnancy

Due to a lack of safety and efficacy studies in pregnant women, the risk to your developing foetus is not known. If you are pregnant, take Troypipera-T 4.5 Injection only if prescribed by your doctor.

Breast-feeding

Troypipera-T 4.5 Injection passes into breast milk in very low quantities and may cause diarrhoea in your breastfed infant. If you are breastfeeding, consult your doctor.
General warnings

Antibiotic resistance

Antibiotic resistance is a condition in which the antibiotic is not effective against the bacteria. This can be avoided by completing the entire course of treatment with Troypipera-T 4.5 Injection as prescribed by your doctor.

Diarrhoea

Troypipera-T 4.5 Injection can cause diarrhoea because it may also kill the helpful bacteria in your stomach or intestine. Get emergency medical help if you experience severe watery or bloody diarrhoea. Consult your pharmacist/doctor before taking anti-diarrhoeal medication.

Skin reactions

Troypipera-T 4.5 Injection may cause allergic skin reactions. Inform your doctor if you experience any signs and symptoms of skin reaction such as skin rash, severe itching/swelling on your face/body.

Intravenous administration

Troypipera-T 4.5 Injection is given as a slow intravenous infusion in a clinic/hospital setting.

Use in children

Troypipera-T 4.5 Injection is not recommended for use in children below 2 years of age due to a lack of safety and efficacy data.

Seizures

Troypipera-T 4.5 Injection should be given with caution if you have any pre-existing kidney problems or a history of seizures (fits) due to the increased risk of a seizure attack.

Bleeding problems

Troypipera-T 4.5 Injection may increase your risk of bleeding. This risk is especially higher if you have any pre-existing kidney problems. Your doctor may recommend tests (prothrombin time) to monitor your bleeding problems.

Low white blood cell count

Troypipera-T 4.5 Injection may increase your risk of leukopenia and neutropenia (decreased number of leukocytes and neutrophils, a type of white blood cells), especially with prolonged therapy. Your blood cell count will be closely monitored.

Driving or operating machinery

Troypipera-T 4.5 Injection may cause sleeplessness. Do not drive or operate machines if you experience any symptoms that may affect your mental alertness.

Missed Dose

Since Troypipera-T 4.5 Injection is given by a qualified healthcare professional in the clinic/hospital setting, the likelihood of a missed dose is very low.

Overdose

Since Troypipera-T 4.5 Injection is given in the hospital or clinical setting by a qualified healthcare professional, the likelihood of an overdose is very low.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Live vaccines

Methotrexate

Doxycycline

Ethinyl Estradiol

Warfarin

Disease interactions

Kidney Disease

Troypipera-T 4.5 Injection is eliminated by kidneys and should be used with caution if you have pre-existing kidney problems due to the increased risk of side effects, resulting from the accumulation of this medicine in your body. Your kidney function will be closely monitored and the dose may be adjusted based on your clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
Troypipera-T 4.5 Injection is given by a qualified healthcare professional in a clinic/hospital setting. Follow all the instructions given by your doctor. If you experience any redness/pain/swelling at the site of injection that becomes bothersome, inform your doctor immediately. Troypipera-T 4.5 Injection may lower your white blood cell count. Periodic monitoring of your blood cell count is recommended. Troypipera-T 4.5 Injection may increase your risk of seizures (fits). Inform your doctor if you have any history of seizures before starting treatment with this medicine.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

May cause sleepiness

How it works
Troypipera-T 4.5 Injection is a combination of Piperacillin and Tazobactam. Piperacillin works by preventing the formation of bacterial cell walls, the outer covering required for cells to stay alive and thereby effectively killing the bacteria. Tazobactam works by preventing bacteria from destroying Piperacillin. Thus, this combination is effective against an extended range of bacteria.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Penicillin Beta-Lactam Antibiotics, Beta-lactamase inhibitors

Schedule

Schedule H

Drugs, H., 2021. Piperacillin and Tazobactam Injection: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 22 September 2021].

https://medlineplus.gov/druginfo/meds/a694003.html>

Medicines.org.uk. 2021. Tazocin 4 g / 0.5 g powder for solution for infusion - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 22 September 2021].

https://www.medicines.org.uk/emc/product/1267/smpc>

Medicines.org.uk. 2021. [online] Available at: < [Accessed 22 September 2021].

https://www.medicines.org.uk/emc/files/pil.1267.pdf>

Accessdata.fda.gov. 2021. [online] Available at: < [Accessed 22 September 2021].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/050684s88s89s90_050750s37s38s39lbl.pdf>

Dailymed.nlm.nih.gov. 2021. DailyMed - PIPERACILLIN AND TAZOBACTAM injection, powder, lyophilized, for solution. [online] Available at: < [Accessed 22 September 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=9b682c66-61c6-4ade-baf4-9d68911a16b8>
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Information on this page was last updated on 25 Oct 2021

Disclaimer

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