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Thioril 25 mg Tablet

Manufactured byTorrent Pharmaceuticals Ltd.
ContainsThioridazine
Description
Thioril 25 mg Tablet is an antipsychotic medicine that is used to control symptoms of schizophrenia. This medicine should be started at low doses and the doses should be increased gradually. This medicine should be used in schizophrenia patients only when other alternative treatment options are ineffective.

Side effects

Major & minor side effects for Thioril 25 mg Tablet

  • Drowsiness
  • Dry mouth
  • Constipation
  • Agitation
  • Weight gain
  • Skin rash
  • Muscle spasm
  • Headache
  • Irregular heartbeat
  • Tremors

Uses of Thioril 25 mg Tablet

What is it prescribed for?

  • Schizophrenia
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for this medicine to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The effect of this medicine lasts for an average duration of 8 to 12 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended with this medicine due to an increase in the risk of dizziness, seizures, and irregular heartbeats. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery while taking this medicine.
  • Is this a habit forming medicine?
    No habit forming tendency has been reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to Thioril 25 mg Tablet.

Severe central nervous system depression

This medicine is not recommended for use in patients with severe central nervous system depression due to an increase in the risk of serious adverse effects.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

Neuroleptic Malignant Syndrome

Thioril 25 mg Tablet should be discontinued immediately if the patient develops Neuroleptic Malignant Syndrome, characterized by an increase in the body temperature, muscle rigidity, and altered consciousness.

Tardive dyskinesia

Thioril 25 mg Tablet may cause involuntary movements of tongue, lips, and face. Inform the doctor on priority if symptoms like these appear. Appropriate dose adjustments or replacement with a suitable alternative should be done based on the clinical condition.

Blood cells count

Thioril 25 mg Tablet may reduce the blood cell count, especially WBCs (neutrophils). Any symptoms of fever or weakness during the treatment should be reported to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative should be done based on the clinical condition.

Missed Dose

Take the missed dose as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Concurrent use of ethanol and phenothiazines may result in additive CNS depression and psychomotor impairment.

Instructions

Consumption of alcohol is not recommended with this medicine due to an increase in the risk of dizziness, seizures, and irregular heartbeats. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery while taking this medicine.
Interaction with Medicine

Enalapril

Metformin

Propranolol

Fluoroquinolone antibiotics

Disease interactions

Dementia

This medicine is not recommended for use in patients with dementia-related psychosis since it increases the risk of life-threatening conditions like heart failure and infectious diseases like pneumonia. An alternate medicine should be considered based on the clinical condition.

Cardiovascular disease

This medicine is known to lower the blood pressure and may cause dizziness after the first dose of injection. It should be used with extreme caution in patients with a history of heart diseases or active heart disease. Close monitoring of blood pressure and heart function is necessary while receiving this medicine.
Food interactions
Information not available.
Lab interactions
Information not available.
Take Thioril 25 mg Tablet as advised by the doctor. Do not consume larger amounts than prescribed. Patients with heart diseases and depression are not recommended to receive this medicine. Do not consume alcohol while taking this medicine. It is advised that you do not operate heavy machinery or drive a vehicle while receiving the medicine.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Causes sleepiness

How it works
It works by binding to the receptors and blocking the release of the chemical substances that cause psychotic symptoms.
Legal Status

Approved

Approved

Unknown

Approved

Classification

Category

Phenothiazine antipsychotics

Schedule

Schedule H

Thioridazine - DrugBank [Internet]. Drugbank.ca. 2017 [cited 17 July 2017]. Available from:

https://www.drugbank.ca/drugs/DB00679

DailyMed - Thioridazine hydrochloride tablet, film coated [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 17 July 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=56b3f4c2-52af-4947-b225-6808ae9f26f5

Prescribing medicines in pregnancy database [Internet]. Therapeutic Goods Administration (TGA). 2017 [cited 17 July 2017]. Available from:

https://www.tga.gov.au/prescribing-medicines-pregnancy-database

[Internet]. Toxnet.nlm.nih.gov. 2017 [cited 17 July 2017]. Available from:

https://toxnet.nlm.nih.gov/cgi-bin/sis/search2/f?./temp/~0WIkJO:1
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Information on this page was last updated on 5 Jan 2018

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