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Tacroren 0.5 MG Capsule

Manufactured byLa Renon Healthcare
ContainsTacrolimus
Description
Tacroren 0.5 MG Capsule is an immuno-suppressant medicine. It is used to prevent organ rejection ((when your body's immune system treats the transplanted organ as a foreign object and attacks it) after a kidney, liver, or heart transplantation. It works by decreasing the activity of the immune system (defence system rejecting foreign substances) and helps in preventing the rejection of the transplanted organ by the body. Tacroren 0.5 MG Capsule has some side effects like headache, nausea, vomiting, diarrhoea, constipation, dizziness, back or joint pain, loss of appetite, etc. These side effects may subside by themselves. However, consult your doctor if they bother you for a longer time or worsen. Avoid taking this medicine if you are allergic to it. Tacroren 0.5 MG Capsule should be taken on an empty stomach, one hour before or two hours after a meal. Follow all the instructions given by your doctor. Avoid taking more than the recommended dose. Take it every day at the same time for the ease of remembering and for better results. Tacroren 0.5 MG Capsule may not be suitable for everyone. Inform your doctor if you have liver, heart, or kidney problems, high blood pressure, or diabetes. Also, inform your doctor about your ongoing medications to avoid undesired effects. Consult your doctor if you are pregnant or are breastfeeding.

Side effects

Major & minor side effects for Tacroren 0.5 MG Capsule

  • Headache
  • Diarrhoea
  • Dizziness
  • Nausea or Vomiting
  • Swelling of feet or lower legs
  • Blurred vision
  • Sweating
  • Weight loss
  • Back pain
  • Joint pain
  • Scaly skin
  • Loss of appetite

Uses of Tacroren 0.5 MG Capsule

What is it prescribed for?

  • Organ Transplant - Rejection Prophylaxis
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The time taken for Tacroren 0.5 MG Capsule to show its effect is not clinically determined
  • How long do the effects of this medicine last?
    The amount of time for which Tacroren 0.5 MG Capsule remains active in your body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported with Tacroren 0.5 MG Capsule.
  • Can this medicine be taken during pregnancy?
    Tacroren 0.5 MG Capsule is not recommended for use during pregnancy as it may cause harm to the developing foetus. Hence, consult your doctor if you are pregnant.
  • Can this medicine be taken while breast-feeding?
    Tacroren 0.5 MG Capsule is not recommended for use while breastfeeding as it may pass into the breastmilk. Hence, consult your doctor if you are breastfeeding.

Allergy

Avoid taking Tacroren 0.5 MG Capsule if you are allergic to it. Serious allergic reactions to this medicine are rare. However, seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc.
Warnings for special population

Pregnancy

Tacroren 0.5 MG Capsule is not recommended for use during pregnancy as it may cause harm to the developing foetus. Hence, consult your doctor if you are pregnant.

Breast-feeding

Tacroren 0.5 MG Capsule is not recommended for use while breastfeeding as it may pass into the breastmilk. Hence, consult your doctor if you are breastfeeding.
General warnings

Lymphoma

Tacroren 0.5 MG Capsule should be used with caution as long-term treatment with this medicine may increase the risk of lymphoma (cancer that begins in infection-fighting cells of the immune system).

Serious infections

Tacroren 0.5 MG Capsule should be used with caution as it can weaken your immune system and make you prone to serious infections. Inform your doctor if you experience sore throat, cough, fever, skin infection, etc.

Kidney impairment

Tacroren 0.5 MG Capsule should be used with caution if you have kidney problems as it may increase the risk of kidney toxicity. Your doctor may adjust the dose of this medicine based on your clinical condition.

Hypertension

Hypertension refers to high blood pressure. Tacroren 0.5 MG Capsule should be with caution if you have hypertension, as this medicine may lead to an elevation in blood pressure and further worsen your condition. Monitor your blood pressure regularly while you are taking this medicine.

Hyperkalaemia

Tacroren 0.5 MG Capsule should be used with caution as it may cause hyperkalaemia (an increase in the blood potassium levels). This may further lead to an irregular heartbeat. Your doctor may suggest tests to closely monitor your potassium level if necessary while you are taking this medicine.

Driving vehicles or operating machines

Tacroren 0.5 MG Capsule may cause blurred vision or dizziness. Hence, avoid driving vehicles or operating machines if you experience such symptoms.

Liver Impairment

Tacroren 0.5 MG Capsule is broken down in the liver. Hence, it should be used with caution if you have liver problems, as it may increase the accumulation of this medicine in the body. This may increase the risk of undesired effects. Your doctor may adjust the dose of this medicine based on your clinical condition.

QT prolongation

QT prolongation is a condition in which your heart muscles take a longer time to recharge between a heartbeat. Tacroren 0.5 MG Capsule may cause QT prolongation and should be used with caution if you have heart problems. Your doctor may suggest tests to monitor the functioning of your heart and electrolyte levels during treatment with this medicine.

Vaccination

Consult your doctor before getting vaccinated during treatment with Tacroren 0.5 MG Capsule. This medicine can alter your body's response to the vaccine and the vaccine may not work well.

Skin cancer

Tacroren 0.5 MG Capsule should be used with caution as it may increase the risk of skin cancer. Hence, limit your exposure to sunlight and UV light by wearing protective clothing or using sunscreen.

Missed Dose

Try not to skip a dose of Tacroren 0.5 MG Capsule. If you miss a dose, take it as soon as you remember. If it is time for your next dose, skip the missed one. Do not double the dose to compensate for a missed one.

Overdose

Never take more than the recommended dose. Seek emergency medical attention in case of an overdose with Tacroren 0.5 MG Capsule.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Amlodipine

Carbamazepine

Live attenuated vaccines and related products

Neomycin

Piroxicam

Cyclosporine

Disease interactions

Diabetes Mellitus

Tacroren 0.5 MG Capsule should be used with caution as it has been reported to cause a condition called post-transplant insulin-dependent diabetes mellitus (high blood sugar levels after organ transplantation). Your doctor may suggest tests to closely monitor your blood sugar levels and recommend treatment with Insulin (a medicine to lower blood sugar levels) based on your clinical condition.
Food interactions
Avoid consuming grapefruit juice during treatment with Tacroren 0.5 MG Capsule as it may increase the amount of this medicine in your body. This may increase the risk of serious side effects.
Lab interactions
Information not available.
Take Tacroren 0.5 MG Capsule as instructed by your doctor. Do not break, chew, or crush the capsule. Avoid taking more than the prescribed dose. For the ease of remembering, take it around the same time every day. Tacroren 0.5 MG Capsule may increase the risk of skin cancer. Hence, limit your exposure to sunlight and UV light by wearing protective clothing or using sunscreen during treatment with this medicine. Tacroren 0.5 MG Capsule may increase your risk of infections. Consult your doctor if you experience fever, sore throat, cough, mouth sores, etc. Avoid driving vehicles or operating machines if you feel dizzy or experience blurred vision during treatment with this medicine. Consult your doctor before getting vaccinated during treatment with Tacroren 0.5 MG Capsule. This medicine can alter your body's response to the vaccine and the vaccine may not work well.
Miscelleneous

To be taken on an empty stomach

To be taken as instructed by doctor

May cause sleepiness

How it works
Tacroren 0.5 MG Capsule works by decreasing the activity of your immune system and helps in preventing the rejection of the transplanted organ by the body.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Calcineurin inhibitors, Immunosuppressive agents

Schedule

Schedule H

Medicines.org.uk. 2021. Prograf 0.5mg Hard Capsules - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 19 November 2021].

https://www.medicines.org.uk/emc/product/6720#gref>

Drugs, H., 2021. Tacrolimus: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 19 November 2021].

https://medlineplus.gov/druginfo/meds/a601117.html>

Accessdata.fda.gov. 2021. [online] Available at: < [Accessed 19 November 2021].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/050709s031lbl.pdf>
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Information on this page was last updated on 8 Mar 2022

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