Sodium Bicarbonate

Description

The primary ingredient of Sodium Bicarbonate is available as both oral and parenteral forms. This medicine is used as an antacid which helps in neutralizing stomach acid during indigestion and heartburn. It acts as an alkalinizing agent and used in the treatment of metabolic acidosis resulting from many clinical conditions. It is also indicated in severe diarrhea and in the treatment of certain medicine intoxications to diminish the kidney toxicity.

Side effects

Major & minor side effects for Sodium Bicarbonate

  • Headache
  • Nausea or Vomiting
  • Muscle pain or twitching
  • Slow breathing
  • Increased thirst
  • Stomach cramps
  • Frequent urge to urinate
  • Loss of appetite
  • Unpleasant taste
  • Mood or mental changes
  • Unsual tiredness or weakness
  • Dry mouth

Uses of Sodium Bicarbonate

What is it prescribed for?

  • Metabolic Acidosis
  • Diabetic ketoacidosis
  • Urine alkalinization
  • Dyspepsia
  • Hyperkalemia
  • Asystole
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Concerns

Commonly asked questions

  • Onset of action
    Parenteral form: The effect of this medicine can be observed within 15 minutes on an intravenous administration of the dose. Oral form: The amount of time taken by this medicine to show its effect is subject to vary based on the individual, strength, and form of administration.
  • Duration of effect
    Parenteral form: The effect of this medicine lasts for an average duration of 1 to 2 hours after an intravenous administration of the dose. Oral form: The amount of time for which this medicine remains effective is subject to vary based on the individual, strength, and form of administration.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. The risks and benefits should be discussed with the doctor before taking/receiving this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking/receiving this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to sodium bicarbonate or any other inactive ingredients present along with it.

Metabolic or respiratory alkalosis

This medicine is not recommended for use when the patient with metabolic or respiratory alkalosis due to the risk of worsening of the patient's condition.

Hypocalcemia

This medicine is not recommended for use in patients with hypocalcemia (low levels of calcium in the blood) due to the risk of worsening of the patient's condition.

Hypochloremia

This medicine is not recommended for use in patients with excessive chloride loss by vomiting or gastrointestinal suctioning due to the risk of worsening of the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. The risks and benefits should be discussed with the doctor before taking/receiving this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking/receiving this medicine.
General warnings

Electrolytes and acid-base status

It is recommended to monitor the electrolyte levels and acid-base status during and completion of therapy with this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Sodium and water retention

This medicine can induce sodium and water retention and hence should be used with extreme caution in patients with hypernatremia (increased blood sodium levels) or fluid retention due to the risk of worsening of the patient's condition. Close monitoring of the clinical condition, appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Hypokalemia

This medicine may lower the blood potassium levels in some patients. Close monitoring of the blood potassium levels is necessary while receiving this medicine. Appropriate corrective measures, dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Kidney impairment

This medicine should be used with extreme caution in patients with kidney impairment due to the risk of worsening of the patient's condition. Close monitoring of kidney function is recommended while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative might be required in some cases.

Stomach disorders

This medicine should be used with extreme caution in patients with stomach disorders due to the risk of worsening of the patient's condition. Close monitoring of the clinical condition, appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Liver impairment

This medicine should be used with extreme caution in patients with liver impairment due to the risk of worsening of the patient's condition. Close monitoring of liver function is recommended while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative might be required in some cases.

Other uses

Your doctor may prescribe this medicine for indications other than those stated above in certain specific circumstances, especially if other medicines are not effective. All the risks and benefits should be discussed with the doctor in such cases.

Missed Dose

Oral Form: Take the missed dose as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose. Parenteral Form: Since this medicine is usually administered by a qualified healthcare professional in the clinical/hospital setting, the likelihood of a missed dose is very low.

Overdose

Oral Form: Seek emergency medical treatment or contact the doctor in case of an overdose. Parenteral Form: Since this medicine is administered in the hospital setting by a qualified healthcare professional, the likelihood of an overdose is very less. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Bisacodyl

Dolutegravir

Glipizide

Disease interactions

Disease

Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
Oral Form: Take this medicine exactly as prescribed by the doctor. Do not take in larger or smaller quantities than recommended. Consult the doctor if you experience any undesirable side effects. Do not stop the use of this medicine without consulting your doctor. Parenteral Form: This medicine is usually administered in the clinical/hospital setting under the supervision of a qualified healthcare professional. Follow all the instructions given by your doctor. Inform the doctor if you have a known allergy to this medicine. Report all your current medicines as well as your medical conditions to the doctor before receiving this medicine.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Effect on sleep is not established

How it works
As an antacid, this medicine helps in neutralizing stomach acid during indigestion and heartburn. It acts as a buffer against an excess acidic condition of the body by raising blood pH. It increases the urinary pH by increasing the excretion of free bicarbonate ions in the urine.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Alkalizers, Antacids, Minerals and electrolytes, Urinary pH modifiers

Schedule

Schedule H

Sodium bicarbonate - DrugBank [Internet]. Drugbank.ca. 2019 [cited 7 January 2019]. Available from:

https://www.drugbank.ca/drugs/DB01390

[Internet]. 2019 [cited 7 January 2019]. Available from:

https://medsafe.govt.nz/profs/Datasheet/s/SodiumBicarbonateinjAFT.pdf

[Internet]. Fda.gov. 2019 [cited 7 March 2019]. Available from:

https://www.fda.gov/downloads/drugs/drugsafety/drugshortages/ucm561198.pdf

[Internet]. Accessdata.fda.gov. 2019 [cited 7 March 2019]. Available from:

https://www.accessdata.fda.gov/drugsatfda_docs/label/2005/077394lbl.pdf

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Information on this page was last updated on 7 Mar 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.