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Signolol 10 MG Tablet

Manufactured bySigmund Promedica
ContainsPropranolol
Description
Signolol 10 MG Tablet is a beta-blocker medicine that is used for the treatment of hypertension (high blood pressure), angina (chest pain radiating to arms, neck and back), and hypertrophic subaortic stenosis (an abnormal thickening of heart muscle). It is also used to prevent migraine headaches. In some cases, it is also used alone or in combination with other medications to treat heart rhythm disorder (arrhythmia). This medicine attaches to the heart and blocks certain molecules that trigger receptors. These receptors are responsible for inducing heartbeat, thus blocking it makes the heartbeat slow and lowers blood pressure. Your doctor may prescribe you a dose based on the clinical response to the medicine. The common side effects of Signolol 10 MG Tablet are tiredness, unusual weakness, nausea, vomiting and diarrhoea. Most of these side effects are short term and may improve as the body gets habituated to them. If any of these side effects persist or worsen, consult your doctor at the earliest. Do not take this medicine if you are allergic to it. You can take Signolol 10 MG Tablet with or without food. Take this medicine as directed by your doctor and do not stop on your own even you feel better. Discuss all the known illnesses such as asthma, kidney disease, liver disease, etc., with your doctor. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding mother. Your doctor may advise certain tests to make sure whether the medicine is working properly or not.

Side effects

Major & minor side effects for Signolol 10 MG Tablet

  • Dizziness and lightheadedness
  • Diarrhoea
  • Difficulty in breathing
  • Nausea or vomiting
  • Weight gain
  • Constipation
  • Irregular heartbeat
  • Unusual tiredness and weakness

Uses of Signolol 10 MG Tablet

What is it prescribed for?

  • Hypertension
  • Angina pectoris
  • Migraine prevention
  • Hypertrophic subaortic stenosis
  • Heart attack
  • Pheochromocytoma
  • Arrhythmias
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The time Signolol 10 MG Tablet takes to show its effect is not known. However, it may vary based on the intended use.
  • How long do the effects of this medicine last?
    The average time for which Signolol 10 MG Tablet stays in the body is not known. However, it may vary based on the intended use.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with Signolol 10 MG Tablet due to the increased risk of side effects such as dizziness, lightheadedness, and fainting. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
  • Is this a habit forming medicine?
    Signolol 10 MG Tablet has no habit forming tendencies.
  • Can this medicine be taken during pregnancy?
    Signolol 10 MG Tablet should not be used in pregnancy as it may increase the risk of foetal death. Discuss all the potential benefits and risks with your doctor before starting the therapy.
  • Can this medicine be taken while breast-feeding?
    Signolol 10 MG Tablet is known to pass into breastmilk. It may alter the heart function in infants. Your doctor may advise you to discontinue breastfeeding or therapy based on the clinical condition. Discuss all the benefits and risks before taking this medicine.

Allergy

Do not take Signolol 10 MG Tablet if you have a known allergy to Propranolol or any other inactive ingredients present along with the formulation. Seek medical attention if you come across any allergic reactions such as skin rash, hives, swelling (face, lips, tongue, etc.), breathing difficulty, etc.

Uncompensated congestive heart failure

Uncompensated congestive heart failure is a syndrome in which the functional and structural change in the heart leads to the inability of the heart to pump and accommodate the blood. Signolol 10 MG Tablet is not recommended for use in patients with this heart condition as it may increase the risk of complete loss of heart function, thus worsening the condition.

Cardiogenic shock

Cardiogenic shock is a sudden drop of blood pressure in the body. The heart loses its ability to pump enough blood to meet the demands of the body. Signolol 10 MG Tablet is not recommended for use in patients with cardiogenic shock as it may worsen the heart condition leading to other complications.

Severe bradycardia

Bradycardia is a heart condition in which the heartbeat becomes very low than normal. Using Signolol 10 MG Tablet may lead to provoke low heartbeat and may increase the risk of heart attack or stroke.

Heart block greater than first degree

A heart block is a condition in which the electrical signals do not pass or blocks in the heart which slows or stops the blood pumping phenomena of the heart. Signolol 10 MG Tablet when used in this condition may worsen the blood pumping ability of the heart and also increases the risk of a heart attack.
Warnings for special population

Pregnancy

Signolol 10 MG Tablet should not be used in pregnancy as it may increase the risk of foetal death. Discuss all the potential benefits and risks with your doctor before starting the therapy.

Breast-feeding

Signolol 10 MG Tablet is known to pass into breastmilk. It may alter the heart function in infants. Your doctor may advise you to discontinue breastfeeding or therapy based on the clinical condition. Discuss all the benefits and risks before taking this medicine.
General warnings

Hyperthyroidism

Taking Signolol 10 MG Tablet in hyperthyroid patients may mask the symptoms of hyperthyroidism. It may also alter the thyroid function test. If undiagnosed and untreated, this condition may lead to a thyroid storm (a life-threatening condition in which there is an excess release of thyroid hormone (TSH) leading to toxicity in the body). Close monitoring of thyroid function tests and clinical conditions is indicated.

Sports

It is advised to not indulge in certain sports while consuming Signolol 10 MG Tablet. Archery, racing, shooting, and other high-risk sports should be avoided. Sportspersons should refer to the list of banned medicines published by the World Anti-Doping Agency while participating in specific sports events.

Driving or operating machinery

Signolol 10 MG Tablet may cause fatigue, weakness, or dizziness in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms.

Missed Dose

Take the missed dose of Signolol 10 MG Tablet as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume at the scheduled time. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case you suspect Signolol 10 MG Tablet overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with Signolol 10 MG Tablet due to the increased risk of side effects such as dizziness, lightheadedness, and fainting. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
Interaction with Medicine

Amlodipine

Diltiazem

Lidocaine

Aminophylline

Formoterol

Epinephrine

Nonsteroidal anti-inflammatory medicines

Disease interactions

Asthma

Signolol 10 MG Tablet is not recommended for use in patients with a history of bronchial asthma (swelling and narrowing of airway path with overproduction of mucous) or chronic obstructive pulmonary disease (a chronic inflammatory lung disease that causes obstructed airflow from the lungs) as it may increase the risk of narrowing of the airway path. Close monitoring of the lungs function is indicated.

Diabetes

Signolol 10 MG Tablet may mask the monitory signs of hypoglycemia (low blood sugar levels) such as blood pressure, pulse rate, etc., especially in patients taking insulin. Close monitoring of blood sugar levels is indicated in these patients.

Glaucoma

Signolol 10 MG Tablet when used in glaucoma may increase the risk of decreased eye pressure. It will lead to a worsening of glaucoma and may also lead to open-angle glaucoma. hence, it is not recommended to use in this condition.

Liver diseases

Signolol 10 MG Tablet should be used with caution in patients suffering from mild to moderate liver diseases due to the increased risk of liver cirrhosis (scarring of the healthy liver tissue leading to irreversible liver damage). Close monitoring of liver function is indicated.

Kidney Diseases

Caution should be exercised while taking Signolol 10 MG Tablet in kidney disease patients as it may increase the risk of Signolol 10 MG Tablet accumulation in the kidneys as this medicine is excreted through kidneys. Close monitoring of kidney function is necessary while receiving this medicine.
Food interactions
Taking Signolol 10 MG Tablet with multivitamins should be avoided since it may decrease the effects of the medicine. A time gap of at least 2 hours should be maintained between the administration of multivitamins with minerals and this medicine to avoid their interaction.
Lab interactions
Information not available.
Take Signolol 10 MG Tablet exactly as instructed by the doctor. You can take this medicine with or without food. Do not take in larger or smaller amounts than prescribed. Seek emergency medical treatment in case of any severe side effects. Ensure that the course of treatment is completed. Do not stop the use of this medicine without consulting your doctor. Do not break, crush or chew the capsule. Take the capsule immediately after peeling from the strip.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Effect on sleep is not established

How it works
Signolol 10 MG Tablet works by reducing the blood pressure by blocking the beta2 receptors present on the heart which are responsible for the increased blood pressure. It also relaxes the blood vessels that enhance proper blood flow in the body.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Group II antiarrhythmics, Non-cardioselective beta blockers

Schedule

Schedule H

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https://go.drugbank.com/drugs/DB00571>

Dailymed.nlm.nih.gov. 2021. DailyMed - PROPRANOLOL HYDROCHLORIDE tablet. [online] Available at: < [Accessed 8 July 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=ab9e5678-db53-4354-998a-ed8bf1d33e90>

Drugs, H., 2021. Propranolol (Cardiovascular): MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 8 July 2021].

https://medlineplus.gov/druginfo/meds/a682607.html>

Accessdata.fda.gov. 2021. [online] Available at: < [Accessed 8 July 2021].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/018553s037lbl.pdf>

Medicines.org.uk. 2021. Propranolol 40mg Film-coated tablets - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 8 July 2021].

https://www.medicines.org.uk/emc/product/11812>
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Information on this page was last updated on 9 Jul 2021

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