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Seretane 2 MG Tablet DT
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Seretane 2 MG Tablet DT

Manufactured byRpg Life Sciences Ltd.
ContainsTrihexyphenidyl
Description
Seretane 2 MG Tablet DT is used in the treatment of Parkinson’s disease (a nervous system disorder that affects the body’s movement). It is also used to treat extrapyramidal symptoms (extreme restlessness or involuntary muscle spasm) caused by certain medicines. Seretane 2 MG Tablet DT works by blocking the action of a natural chemical substance in the body. Thus, it helps restore muscle control and reduces stiffness. Seretane 2 MG Tablet DT shows common side effects such as dry mouth, headache, constipation, vomiting, and stomach upset. These side effects usually subside with time. If they persist or become worse, consult your doctor for further assistance. Avoid driving vehicles or operating heavy machines while taking this medication as it can cause dizziness and blurred vision. Seretane 2 MG Tablet DT is a prescription medicine. It may be taken with food to reduce stomach upset. Disperse the tablet in a glass of water and consume. Take it at the same time every day for ease of remembering. Follow all the instructions given by your doctor while taking the medication. Do not take more than the recommended dose. Avoid abrupt discontinuation of this medicine as it may worsen your condition. Seretane 2 MG Tablet DT is not recommended if you are allergic to it. Avoid taking this medication if you have narrow-angle glaucoma (an eye condition that causes increased pressure inside the eyes). Inform your doctor if you have gastrointestinal obstruction, heart problems, high blood pressure, or urinary problems. Also, inform your doctor about your current medications to avoid undesired effects. Seretane 2 MG Tablet DT is not recommended for use in children below 18 years of age. Consult your doctor if you are pregnant or are breastfeeding before taking this medicine.
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Side effectsConcernsUsage

Substitutes

List of substitutes for Seretane 2 MG Tablet DT

Bexol 2 MG Tablet DT
Intas Pharmaceuticals Ltd.

Side effects

Major & minor side effects for Seretane 2 MG Tablet DT

  • Abdominal pain
  • Constipation
  • Dry mouth
  • Difficulty in passing urine
  • Skin rash
  • Dizziness
  • Nausea and Vomiting
  • Nervousness

Uses of Seretane 2 MG Tablet DT

What is it prescribed for?

  • Parkinson's disease
  • Drug-induced Extrapyramidal Symptoms
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The time required for Seretane 2 MG Tablet DT to show its action is not clinically known.
  • How long do the effects of this medicine last?
    The time duration for which Seretane 2 MG Tablet DT remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended while taking Seretane 2 MG Tablet DT as it may increase the risk of side effects like dizziness and drowsiness.
  • Is this a habit forming medicine?
    No habit-forming tendency has been reported for Seretane 2 MG Tablet DT.
  • Can this medicine be taken during pregnancy?
    Seretane 2 MG Tablet DT is not recommended for use during pregnancy unless necessary. Therefore, consult your doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    Seretane 2 MG Tablet DT is not recommended for use while breastfeeding unless necessary. The risks and benefits should be discussed with your doctor before taking this medicine.

Allergy

Seretane 2 MG Tablet DT is not recommended if you are allergic to it. Seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc.

Narrow angle glaucoma

Narrow-angle glaucoma is an eye condition that occurs due to the blockage of the drainage canals (the structure inside the eye that allows fluid to drain normally from the eye), causing increased pressure inside the eye. Seretane 2 MG Tablet DT is not recommended for use if you have narrow-angle glaucoma, as it can make your condition worse.
Warnings for special population

Pregnancy

Seretane 2 MG Tablet DT is not recommended for use during pregnancy unless necessary. Therefore, consult your doctor before taking this medicine.

Breast-feeding

Seretane 2 MG Tablet DT is not recommended for use while breastfeeding unless necessary. The risks and benefits should be discussed with your doctor before taking this medicine.
General warnings

Neuroleptic Malignant Syndrome

Neuroleptic malignant syndrome is a rare life-threatening condition characterised by fever, an abnormally high body temperature, muscle rigidity, altered mental status, irregular pulse or blood pressure, etc. Caution should be maintained while taking Seretane 2 MG Tablet DT, as it can worsen your condition. Consult your doctor before taking the medication if you have neuroleptic malignant syndrome.

Infectious Diarrhoea

Seretane 2 MG Tablet DT may decrease the elimination of bacteria that cause diarrhoea and prolong or worsen diarhroea. Therefore, this medicine should be used with caution if you have infections diarrhoea, particularly if followed by a high fever and pus/blood in the stool. Inform the doctor if you are having severe diarrhoea or taking antibiotics before starting treatment with this medication.

Psychotic symptoms

Seretane 2 MG Tablet DT may cause psychotic symptoms like confusion, delusions, and hallucination. It should be used with caution in elderly people due to an increase in the risk of these symptoms.

Withdrawal effect

Seretane 2 MG Tablet DT should not be discontinued abruptly as it can cause withdrawal symptoms such as a headache, anxiety, seizures (abnormal behaviour and uncontrolled movements of the body), etc. Your doctor may suggest an appropriate regimen to gradually stop the treatment.

Use in children

Seretane 2 MG Tablet DT is not recommended for use in children less than 18 years of age as the safety and efficacy data are not clinically established.

Driving vehicles or operating machines

Seretane 2 MG Tablet DT may cause blurred vision or dizziness. Hence, it is advised not to drive vehicles or operate machines while taking this medication.

Tardive dyskinesia

Tardive dyskinesia is an abnormal movement of some body parts (face, tongue, and jaw). Seretane 2 MG Tablet DT should be used with extreme caution if you have tardive dyskinesia, as it may further worsen your condition.

Missed Dose

Try not to miss any dose of Seretane 2 MG Tablet DT. In case you miss a dose, take it as soon as you remember. If it is time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

Avoid taking more than the recommended dose. Seek emergency medical treatment in case of an overdose of Seretane 2 MG Tablet DT.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended while taking Seretane 2 MG Tablet DT as it may increase the risk of side effects like dizziness and drowsiness.
Interaction with Medicine

Atenolol

Clobazam

Pregabalin

Tramadol

Bisoprolol

Disease interactions

Arrhythmias

Arrhythmia is the abnormal rhythm of the heart. Seretane 2 MG Tablet DT should be used with caution if you have arrhythmia as it may further worsen your condition.

Autonomic neuropathy

Autonomic neuropathy occurs when there is damage to the nerves that control the internal organs, causing abnormality in involuntary body functions such as heart rate, perspiration, digestion, bladder function, etc. Seretane 2 MG Tablet DT should be used with caution if you have autonomic neuropathy, as it can further aggravate the condition.

Psychosis

Psychosis is a mental condition that causes disconnection from reality. Seretane 2 MG Tablet DT should be used with caution in such cases, as it can further worsen the condition.

Hypertension

Seretane 2 MG Tablet DT may cause an increase in blood pressure. Hence, it should be used with caution if you have hypertension (abnormally high blood pressure). Monitor your blood pressure regularly while you are taking this medicine.

Obstructive uropathy

Obstructive uropathy is a disorder of the urinary tract. It leads to obstruction in normal urinary flow, causing retention of urine in the urinary bladder (an organ that stores urine). Seretane 2 MG Tablet DT should be used with caution if you have partial obstructive uropathy, as it may further aggravate your condition.

Gastrointestinal obstruction

Gastrointestinal obstruction is a partial or complete blockage of the intestine that prevents food or liquid from passing through it. Seretane 2 MG Tablet DT should be used with caution in case of gastrointestinal obstruction. This medicine can reduce muscle mobility and cause delayed emptying of food from the digestive tract. Thus it may further worsen your condition.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Seretane 2 MG Tablet DT should be taken with food to reduce stomach upset. Before taking, disperse the tablet in a glass of water and then consume it. Do not take more than the recommended dose. Follow all the instructions given by your doctor while taking the medication. Do not discontinue Seretane 2 MG Tablet DT without consulting your doctor, as it can cause withdrawal symptoms. Seretane 2 MG Tablet DT can cause dryness of the mouth, nose, and throat. You can use sugarless candy, mints, or chewing gum for temporary relief from dryness. Consult your doctor before taking the medication if you are pregnant or breastfeeding. Avoid driving vehicles or operating machines while taking this medicine, as it can make you feel dizzy or drowsy.
Miscelleneous

To be taken with food

To be taken as instructed by doctor

May cause sleepiness

How it works
Seretane 2 MG Tablet DT works by blocking the activity of a natural chemical substance that causes abnormality in muscle movement. Thus it restores muscle control, reduces stiffness, and improves movements.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Anticholinergic antiparkinson agents

Schedule

Schedule H

Drugs, H., 2022. Trihexyphenidyl: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: [Accessed 29 June 2022].

https://medlineplus.gov/druginfo/meds/a682160.html#:~:text=Trihexyphenidyl%20comes%20as%20a%20tablet,or%20four%20times%20a%20day.

Pubchem.ncbi.nlm.nih.gov. 2022. Trihexyphenidyl. [online] Available at: [Accessed 5 July 2022].

https://pubchem.ncbi.nlm.nih.gov/compound/Trihexyphenidyl

Mayoclinic.org. 2022. Trihexyphenidyl (Oral Route) Precautions - Mayo Clinic. [online] Available at: 30 June 2022].

https://www.mayoclinic.org/drugs-supplements/trihexyphenidyl-oral-route/precautions/drg-20072660?p=1#:~:text=Trihexyphenidyl%20may%20cause%20dryness%20of,your%20medical%20doctor%20or%20dentist.[Accessed
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Information on this page was last updated on 5 Jul 2022

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