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Retoz 8 MG Tablet MR
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Retoz 8 MG Tablet MR

Manufactured byDr. Reddys Laboratories Ltd.
ContainsEtoricoxib (60 mg) + Thiocolchicoside (8 mg)
Description
Retoz 8 MG Tablet MR is a combination medicine used for the treatment of pain, swelling, and inflammation associated with muscle spasms as well as medical conditions such as rheumatoid arthritis, osteoarthritis, etc. in adults.
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Side effectsConcernsUsageRelated products

Side effects

Major & minor side effects for Retoz 8 MG Tablet MR

  • Itching and skin rash
  • Swelling of face, lips, eyelids, tongue, hands and feet
  • Nausea and Vomiting
  • Yellowing of skin and eyes
  • Photosensitivity
  • Dry mouth
  • Headache
  • Diarrhea
  • Dizziness
  • Stomach pain
  • Difficult and painful breathing
  • Blurred vision
  • Heart rhythm disorders
  • Stevens-Johnson Syndrome

Uses of Retoz 8 MG Tablet MR

What is it prescribed for?

  • Acute inflammatory musculoskeletal disorders with spasm
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for this medicine to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit forming tendency has been reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women due to the increased risk of fetal harm. Your doctor may prescribe a safer alternative based on the clinical condition.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women due to the increased risk of severe adverse effects in the nursing infant. Your doctor may prescribe a safer alternative based on the clinical condition.

Allergy

This medicine is not recommended for use in patients with a known allergy to etoricoxib, any other NSAIDs, thiocolchicoside, or any other inactive ingredient present along with these medicines.

Peptic Ulcer

This medicine is not recommended for use in patients with peptic ulcer disease due to the increased risk of worsening of the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women due to the increased risk of fetal harm. Your doctor may prescribe a safer alternative based on the clinical condition.

Breast-feeding

This medicine is not recommended for use in breastfeeding women due to the increased risk of severe adverse effects in the nursing infant. Your doctor may prescribe a safer alternative based on the clinical condition.
General warnings

Other medicines

Report the use of all your current medicines including herbs and supplements to the doctor to avoid the chances of a possible interaction with this medicine.

Kidney disease

This medicine should be used with caution in patients suffering from a kidney disease or impairment of normal kidney function due to the increased risk of severe adverse effects. Use is not recommended if the impairment is severe.

Drowsiness

Use of this medicine may cause drowsiness, impaired judgment, and impaired normal body movements. Hence, it is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating heavy machinery during treatment with this medicine.

Use in children

This medicine is not recommended for use in children and adolescents.

Use in women of childbearing potential

Women of childbearing potential should adopt appropriate means of contraception to avoid pregnancies during treatment with this medicine. A pregnancy test should be done to rule out pregnancy before beginning treatment. If pregnancy is suspected during treatment, therapy should be discontinued and an alternative treatment option should be considered.

Impairment of fertility

Use of this medicine may cause impairment of fertility in men. Discuss all the risks and benefits with your doctor before taking this medicine.

Stomach ulcer or bleeding

This medicine is not recommended for use in patients with a history of gastrointestinal ulcers and bleeding since it may worsen the patient's condition. Replacement with a suitable alternative should be considered under your doctor's supervision.

Heart disease

This medicine should be used with caution in patients with heart diseases due to the increased risk of adverse effects on the heart, especially after a prolonged use. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Diarrhea and dehydration

This medicine should be used with caution in patients suffering from diarrhea and dehydration since it may worsen the patient's condition. Replacement with a suitable alternative may be required based on the clinical condition.

High blood pressure

This medicine should be used with caution in patients receiving high blood pressure medications since it may lower the effects of these medications. Appropriate dose adjustments may be required based on the clinical condition.

Infections

This medicine should be used with caution in patients receiving medications for infections due to the increased risk of severe adverse effects. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Oral Contraceptive

This medicine should be used with caution in women taking oral contraceptives due to the increased risk of adverse effects. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Lithium

Ramipril

Warfarin

Ethinyl Estradiol

Primaquine

Disease interactions

Fluid Retention and edema

This medicine may cause fluid retention and edema in some patients. Close monitoring of blood pressure, electrolyte levels, and heart function may be required based on the clinical condition. Appropriate dose adjustments or replacement with a suitable alternative may be necessary in some cases.

Heart Disease

This medicine may cause a heart attack, stroke, or other associated symptoms after a prolonged use. This risk is especially higher in patients with a history of heart diseases. Close monitoring of heart function is recommended for such patients. Report any symptoms such as a chest pain, shallow breathing, speech slurring, weakness, etc. to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Liver Disease

This medicine should be used with extreme caution in patients with liver function impairment or active liver diseases due to the increased risk of worsening of the patient's condition. Close monitoring of liver function is necessary while receiving this medicine. Report any incidences of nausea, fever, rashes, dark-colored urine, etc. to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take this medicine exactly as prescribed by the doctor. Do not take in larger or smaller quantities than recommended. Do not take this medicine for longer durations than recommended. Report any unusual symptoms to the doctor immediately. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

To be taken with food

To be taken as instructed by doctor

May cause sleepiness

How it works
Etoricoxib works by reducing the formation of certain substances in the body that cause pain and swelling. Thiocolchicoside works by interacting with certain specific receptors in the central nervous system to prevent muscle contractions and relieve muscle spasms. The combination is thus effective in relieving pain, swelling, and inflammation associated with muscle spasms.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Non-steroidal anti-inflammatory agents, Muscle relaxants

Schedule

Schedule H

[Internet]. 2017 [cited 21 March 2017]. Available from:

https://www.medicines.org.uk/emc/medicine/29136#Productinfo

Etoricoxib | C18H15ClN2O2S - PubChem [Internet]. Pubchem.ncbi.nlm.nih.gov. 2017 [cited 21 March 2017]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/123619#section=Top

[Internet]. 2017 [cited 15 September 2017]. Available from:

http://www.ema.europa.eu/docs/en_GB/document_library/Referrals_document/Thiocolchicoside-containing_medicines/WC500155449.pdf

[Internet]. 2017 [cited 15 September 2017]. Available from:

https://pdfs.semanticscholar.org/6848/43f3f7ad8f393bd283e514563a8a0e8141f1.pdf

[Internet]. 2017 [cited 15 September 2017]. Available from:

https://iasispharma.com/wp-content/uploads/pdf/RELIEF_PIL_ENG.pdf

Thiocolchicoside - DrugBank [Internet]. Drugbank.ca. 2017 [cited 15 September 2017]. Available from:

https://www.drugbank.ca/drugs/DB11582
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Information on this page was last updated on 29 Sep 2017

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