Procyclidine

Description

Procyclidine is used to treat symptoms of Parkinson's disease such as trembling, shakiness, stiff muscles or limbs, unusual head and body movements, etc. It is also used to treat side effects such as trembling, unusual body movements, Parkinson-like symptoms, etc. caused by other medicines.

Side effects

Major & minor side effects for Procyclidine

  • Dry mouth
  • Vomiting
  • Constipation
  • Nausea
  • Abdominal pain
  • Diarrhea
  • Fever
  • Dizziness
  • Headache
  • Anxiety
  • Urinary retention
  • Sleepiness or unusual drowsiness

Uses of Procyclidine

What is it prescribed for?

  • Parkinson's disease
  • Drug-induced Extrapyramidal Symptoms
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Concerns

Commonly asked questions

  • Onset of action
    The amount of time required for this medicine to show its action is not clinically established.
  • Duration of effect
    The effect of this medicine lasts for an average duration of 4 to 8 hours.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to procyclidine or any other inactive ingredient present along with it.

Narrow angle glaucoma

This medicine is not recommended for use in patients with a known history of narrow-angle glaucoma due to the increased risk of worsening of the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

Driving or Operating machinery

Use of this medicine may cause dizziness or drowsiness in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Glaucoma

This medicine is not recommended for use in patients with a known history of narrow-angle glaucoma due to the increased risk of worsening of the patient's condition.

Urinary Retention

This medicine is not recommended for use in patients with a known history of prostate hypertrophy due to the increased risk of worsening of the patient's condition.

Use in children

This medicine is not recommended for use in patients less than 18 years of age since the safety and efficacy of use are not clinically established.

Tardive Dyskinesia

This medicine may cause involuntary movements of the tongue, lips, and face in some patients. Inform the doctor immediately if you have any of these symptoms. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

Liver impairment

This medicine should be used with caution in patients with a known history of liver problems due to the increased risk of severe adverse effects. Report any unusual symptoms to the doctor immediately. Close monitoring of liver function, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition.

Kidney impairment

This medicine should be used with caution in patients with a known history of kidney problems due to the increased risk of severe adverse effects. Report any unusual symptoms to the doctor immediately. Close monitoring of kidney function, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition.

Use in Elderly

This medicine should be used with caution in the elderly patients due to the increased risk of severe side effects. Appropriate dose adjustments, frequent clinical monitoring, or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Loxapine

Aripiprazole

Topiramate

Diphenhydramine

Zonisamide

Hyoscyamine

Disease interactions

Tardive Dyskinesia

This medicine should be used with extreme caution in patients suffering from tardive dyskinesia since it may worsen the patient's condition. Report any unusual symptoms to the doctor on priority. Appropriate patient/caregiver education, close monitoring of the patient's condition, dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition.

Cardiovascular disease

This medicine should be used with caution in patients with a known history of cardiovascular diseases due to the increased risk of worsening of the patient's condition. Close monitoring of cardiac function, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition.

Hypertension

This medicine should be used with caution in patients with a known history of hypertension (high blood pressure) due to the increased risk of worsening of the patient's condition. Close monitoring of blood pressure levels, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
Take this medicine as instructed by your doctor. You are advised to take this medicine after meals. Do not take in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

To be taken after food

To be taken as instructed by doctor

May cause sleepiness

How it works
It works by balancing the levels of certain natural substances in the brain to help relieve the symptoms of Parkinson's disease.
Legal Status

Approved

Approved

Unknown

Approved

Classification

Category

Anticholinergic antiparkinson agents

Schedule

Schedule H

[Internet]. Accessdata.fda.gov. 2018 [cited 6 April 2018]. Available from:

https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/009818s018lbl.pdf

[Internet]. Medsafe.govt.nz. 2018 [cited 6 April 2018]. Available from:

http://www.medsafe.govt.nz/profs/Datasheet/k/Kemadrintab.pdf

Procyclidine - DrugBank [Internet]. Drugbank.ca. 2018 [cited 6 April 2018]. Available from:

https://www.drugbank.ca/drugs/DB00387

Procyclidine [Internet]. Pubchem.ncbi.nlm.nih.gov. 2018 [cited 6 April 2018]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/procyclidine

[Internet]. Tevauk.com. 2018 [cited 6 April 2018]. Available from:

http://www.tevauk.com/mediafile/id/42022.pdf

[Internet]. Medicines.org.uk. 2018 [cited 6 April 2018]. Available from:

https://www.medicines.org.uk/emc/files/pil.8488.pdf

[Internet]. Medicines.org.uk. 2018 [cited 6 April 2018]. Available from:

https://www.medicines.org.uk/emc/files/pil.5460.pdf

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Information on this page was last updated on 24 Apr 2018

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.