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Phenamin 25 MG Injection
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Phenamin 25 MG Injection

Manufactured byIntas Pharmaceuticals Ltd.
ContainsPromethazine
Description
Phenamin 25 MG Injection is an antihistamine with sedative properties which is used to treat allergic reactions such as the runny nose, itching, sneezing, itchy or watery eyes, hives, rashes. It is also used to treat nausea and vomiting caused due to motion sickness and pre and postoperative sedation. This medicine is not recommended in patients with asthma and central nervous system depression disorders.
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Side effectsConcernsUsageRelated products

Substitutes

List of substitutes for Phenamin 25 MG Injection

Phenergan 25 MG Injection
Abbott Healthcare Pvt. Ltd.

Side effects

Major & minor side effects for Phenamin 25 MG Injection

  • Headache
  • Seizures
  • Tremors
  • Skin rash
  • Loss of strength
  • Increased sensitivity of the skin to sunlight
  • Excitation

Uses of Phenamin 25 MG Injection

What is it prescribed for?

  • Allergic Rhinitis
  • Sedation
  • Nausea and vomiting
  • Motion sickness
  • Urticaria
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effect of this medicine can be observed within 3-5 minutes after intravenous administration and 20 minutes after intramuscular administration.
  • How long do the effects of this medicine last?
    The effect of this medicine lasts for an average duration of fewer than 12 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol during treatment with this medicine may increase the risk of severe side effects. These side effects may include confusion, dizziness, nausea, vomiting, weakness, and fainting. It is advised that you should avoid alcohol and not to perform activities which require high mental alertness like driving a vehicle and operating machinery when taking these medicines together.
  • Is this a habit forming medicine?
    No habit forming tendencies has been reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for pregnant women unless absolutely necessary. The benefits and risks should be discussed with the doctor before receiving this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.

Allergy

This medicine is not recommended for use if you have a known allergy to promethazine or any other inactive ingredients present in the formulation.

Asthma

This medicine is not recommended for use in patients with a known history of asthma or any respiratory disease due to the increased risk of serious adverse effects.

Central nervous system depression

This medicine is not recommended for use in patients with a known history of central nervous system depression due to the increased risk of serious adverse effects.
Warnings for special population

Pregnancy

This medicine is not recommended for pregnant women unless absolutely necessary. The benefits and risks should be discussed with the doctor before receiving this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.
General warnings

Use in children

This medicine is not recommended for use in patients less than 2 years of age since the safety and efficacy of use are not clinically established.

Driving or operating machinery

The use of this medicine may cause drowsiness or dizziness in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Other medicines

This medicine may interact with many other medicines and may cause severe adverse effects. Hence, it is advised that you inform the doctor about all your current medicines including any herbs and supplements before beginning treatment with this medicine.

Liver disease

This medicine should be used with extreme caution in patients suffering from liver function impairment or active liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Hypotension

Use of this medicine may cause a fall in blood pressure levels. This risk is especially higher in patients with a history of cardiovascular diseases. Close monitoring of blood pressure is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Missed Dose

Since this medicine is usually administered by a qualified healthcare professional in the clinical/hospital setting, the likelihood of a missed dose is very low. However, it is advised to contact the doctor immediately if you miss a scheduled dose of this medicine.

Overdose

Since this medicine is administered in the hospital setting by a qualified healthcare professional, the likelihood of an overdose is very less. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol during treatment with this medicine may increase the risk of severe side effects. These side effects may include confusion, dizziness, nausea, vomiting, weakness, and fainting. It is advised that you should avoid alcohol and not to perform activities which require high mental alertness like driving a vehicle and operating machinery when taking these medicines together.
Interaction with Medicine

Escitalopram

Tramadol

Antidiabetic medicines

Antihypertnsives

Fosphenytoin

Verapamil

Acebutolol

Amiodarone

Quinidine

Minoxidil Topical

Disease interactions

Cardiovascular disease

This medicine should be used with caution in patients with a known history of cardiovascular disorders due to the increased risk of serious adverse effects. Report any symptoms such as a headache, dizziness, change in heart rate, palpitations, shortness of breathing, etc. to the doctor immediately. Close monitoring of heart function and vital signs, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Impaired liver function

This medicine should be used with caution in patients suffering from liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Impaired kidney function

This medicine should be used with caution in patients suffering from kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Seizure disorders

This medicine should be used with caution in patients with seizure disorders since it may worsen the patient's condition. Close monitoring of the patient's condition is necessary during treatment with this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
This medicine is usually administered in the clinical/hospital setting under the supervision of a qualified healthcare professional. Follow all the instructions given by your doctor. Inform the doctor if you have a known allergy to this medicine. Report all your current medicines as well as your medical conditions to the doctor before receiving this medicine.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

Causes sleepiness

How it works
This medicine works by blocking the action of a certain natural substance in the body.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Antihistamines

Schedule

Schedule H

Promethazine: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2020 [cited 9 April 2020]. Available from:

https://medlineplus.gov/druginfo/meds/a682284.html

Promethazine - DrugBank [Internet]. Drugbank.ca. 2020 [cited 9 April 2020]. Available from:

https://www.drugbank.ca/drugs/DB01069

[Internet]. Medicines.org.uk. 2020 [cited 9 April 2020]. Available from:

https://www.medicines.org.uk/emc/files/pil.1100.pdf

Promethazine HCL 25 mg/mL Injection, USP 1 mL Single Dose Ampule [Internet]. Dailymed.nlm.nih.gov. 2020 [cited 9 April 2020]. Available from:

https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=36c9c162-90af-4f7b-9f56-5d81ed850dbe&type=display

[Internet]. Vaxserve.com. 2020 [cited 9 April 2020]. Available from:

https://www.vaxserve.com/image.cfm?image_type=product_pdf&doc_id=9528

[Internet]. Medsafe.govt.nz. 2020 [cited 9 April 2020]. Available from:

https://www.medsafe.govt.nz/Profs/Datasheet/d/dblPromethazinehydrochlorideinj.pdf
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Information on this page was last updated on 15 Apr 2020

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.