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Padmol Syrup
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Padmol Syrup

Manufactured byMDC PHARMACEUTICALS PVT LTD
ContainsParacetamol (125 mg/5 ml) + Promethazine (5 mg/5 ml)
Description
Padmol Syrup is used for the treatment of fever and minor body pain due to common cold in children. It also provides relief from allergic symptoms due to common colds like runny nose, sneezing, cough, redness of the nose, and watery eyes in children. Padmol Syrup stops the release of a chemical called prostaglandin that causes pain and fever and also histamine responsible for causing allergic symptoms. Side effects of Padmol Syrup are dizziness, sleepiness, diarrhoea, nausea or vomiting. However, Padmol Syrup is banned for use in India due to its severe adverse effects. Padmol Syrup can be taken with or without food. Children with a sensitive stomach should take this medicine with food to prevent stomach discomfort. Administer Padmol Syrup at around the same time every day. If your child vomits this medicine within 30 minutes of administering it, then repeat the dose again.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Padmol Syrup

  • Nausea or Vomiting
  • Mouth ulcers
  • Bloody and cloudy urine
  • Dizziness
  • Skin rash
  • Drowsiness
  • Loss of strength
  • Loss of appetite
  • Increased sensitivity of the skin to sunlight

Uses of Padmol Syrup

What is it prescribed for?

  • Fever
  • Common Cold
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    Padmol Syrup starts its action within 20-30 minutes of administration.
  • How long do the effects of this medicine last?
    Padmol Syrup makes the child feel better for about 12 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit forming tendencies were reported for Padmol Syrup.
  • Can this medicine be taken during pregnancy?
    Padmol Syrup is not recommended for use in pregnant women.
  • Can this medicine be taken while breast-feeding?
    Padmol Syrup is not recommended for use in breastfeeding women.

Allergy

Avoid using Padmol Syrup in children who are previously allergic to it. Seek immediate medical attention if there are any serious allergic symptoms such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, or breathing difficulties.

Severe liver impairment

Children with liver diseases need special dose consideration for Padmol Syrup. This medicine gets converted to its active form in the liver. Therefore, in large amounts of this medicine, more active forms are formed which can damage the liver. The use of this medicine is generally not recommended in children with severe liver diseases because it can further increase the risk of liver damage.
Warnings for special population

Pregnancy

Padmol Syrup is not recommended for use in pregnant women.

Breast-feeding

Padmol Syrup is not recommended for use in breastfeeding women.
General warnings

Skin rash

Padmol Syrup may cause serious skin allergies without any warnings. These events may be fatal in rare cases. Signs and symptoms like rashes, hives, fever, or other allergic symptoms should be reported to the doctor immediately. The treatment should be discontinued if these symptoms appear.

Chronic malnutrition

Malnutrition can increase the risk of Padmol Syrup toxicity in the body. Dose adjustment should be done based on body weight in children.

Missed Dose

Administer the missed dose of Padmol Syrup as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double the dose to make up for the missed dose.

Overdose

Seek medical emergency in case of an overdose with Padmol Syrup.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Carbamazepine

Phenytoin

Sodium Nitrite

Leflunomide

Prilocaine

Chlorpheniramine

Disease interactions

Liver Disease

Children with liver diseases need special dose consideration while using Padmol Syrup. The conversion of Padmol Syrup to its active form happens in the liver. Overdose can produce more active forms and leads to liver damage.

Asthma

Children with asthma may experience allergic reactions while using Padmol Syrup. Hence it is not recommended for use in children with asthma, especially those who had experienced allergic reactions with the use of this medicine.

Heart disease

Long-term use of Padmol Syrup may increase the risk of irregular heartbeat in children with pre-existing heart conditions or heart rhythm disorders. Heart function needs to be monitored in such patients.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Administer Padmol Syrup with or without food. Children with a sensitive stomach should be given this medicine with food to prevent stomach irritation. Never give more than the prescribed dose. Administer this suspension at around the same time daily. If your child vomits this medicine within 30 minutes of administering it, then repeat the dose again.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Causes sleepiness

How it works
Paracetamol works by decreasing the severity of pain signals to the brain. It also stops the release of chemicals called prostaglandins, that increase pain, and body temperature. Promethazine works by stopping the binding of histamine to its receptor and thus helps in relieving the symptoms.
Legal Status

Banned

Unknown

Unknown

Unknown

Classification

Category

Analgesics, Antihistamines

Schedule

Schedule H

Drugbank.ca. 2021. Promethazine | DrugBank Online. [online] Available at: < [Accessed 27 April 2021].

https://www.drugbank.ca/drugs/DB01069>

Drugbank.ca. 2021. Acetaminophen | DrugBank Online. [online] Available at: < [Accessed 27 April 2021].

https://www.drugbank.ca/drugs/DB00316>

Pubchem.ncbi.nlm.nih.gov. 2021. Acetaminophen. [online] Available at: < [Accessed 26 April 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Acetaminophen>

Pubchem.ncbi.nlm.nih.gov. 2021. Promethazine. [online] Available at: < [Accessed 26 April 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Promethazine>
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Information on this page was last updated on 27 May 2021

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