Oxaprozin
Description
Oxaprozin is used to relieve pain, stiffness, tenderness, and swelling in conditions such as osteoarthritis and rheumatoid arthritis. It is also used to treat rheumatoid arthritis symptoms in children aged 6 years and above (juvenile rheumatoid arthritis). Patients are advised to undergo physical therapy and take rest along with this medicine to get the best possible effect.
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Side effects
Major & minor side effects for Oxaprozin
- Skin Rash
- Abdominal pain
- Loss of appetite
- Constipation or diarrhea
- Indigestion
- Heartburn
- Headache
- Tiredness and weakness
- Dizziness
- Ringing in ears
- Nausea and Vomiting
Uses of Oxaprozin
What is it prescribed for?
- Osteoarthritis
- Rheumatoid Arthritis
- Juvenile Rheumatoid Arthritis
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Concerns
Commonly asked questions
- Onset of actionThe amount of time required for this medicine to show its action is not clinically established.
- Duration of effectThe amount of time for which this medicine remains active in the body is not clinically established.
- Safe with alcohol?Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of serious side effects such as severe gastrointestinal bleeding, dizziness, fatigue, weakness, etc.
- Is it habit forming?No habit forming tendency has been reported.
- Usage in pregnancy?This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
- Usage while breast-feeding?This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. If the medicine is used, the infant should be monitored closely for any undesirable side effects. Your doctor may prescribe a safer alternative based on your clinical condition.
Allergy
This medicine is not recommended for use in patients with a known allergy to oxaprozin or any other non-steroidal anti-inflammatory drugs.
Asthma
This medicine is not recommended for use in patients with asthma caused by aspirin or other non-steroidal anti-inflammatory drugs since it may cause a recurrent asthma attack.
Gastrointestinal disorders
This medicine is not recommended for use in patients with gastrointestinal bleeding disorders or active peptic ulcers due to the increased risk of severe gastrointestinal bleeding.
Coronary Artery Bypass Surgery (CABG)
This medicine is not recommended for relieving pain before, during, or after a coronary artery bypass graft (CABG) procedure.
Warnings for special population
Pregnancy
This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
Breast-feeding
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. If the medicine is used, the infant should be monitored closely for any undesirable side effects. Your doctor may prescribe a safer alternative based on your clinical condition.
General warnings
Gastrointestinal adverse effects
This medicine may cause gastrointestinal adverse events including inflammation, bleeding, ulceration, and perforation of the esophagus, stomach, small intestine, or large intestine. Report any unusual symptoms to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
Hypertension
This medicine should be used with caution in patients with a history of hypertension due to the increased risk of worsening of the condition. Close monitoring of the blood pressure is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Hyperkalemia
This medicine may increase serum potassium concentration in some patients. Potassium levels should be checked in patients receiving this medicine Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Anaphylactic reactions
This medicine may cause severe anaphylactic reactions (allergic reactions) in some patients. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be necessary in some cases based on the clinical condition.
Missed Dose
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.
Overdose
Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol
Description
N/A
Instructions
Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of serious side effects such as severe gastrointestinal bleeding, dizziness, fatigue, weakness, etc.
Interaction with Medicine
Digoxin
Methotrexate
Lithium
Aspirin
Warfarin
Glyburide
Disease interactions
Asthma
This medicine is not recommended for use in patients with a known history of NSAID-sensitive asthma. Replacement with a suitable alternative should be done under your doctor's supervision.
Fluid retention
This medicine may cause fluid retention and edema in some patients. Close monitoring of blood pressure, electrolyte levels, and heart function may be required based on the clinical condition. Appropriate dose adjustments or replacement with a suitable alternative may be necessary in some cases.
Gastro-Intestinal toxicity
This medicine may cause damage to the stomach, intestines, liver, etc., especially on prolonged use. Report any symptoms such as chronic indigestion, blood in stool or vomit, etc. to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
Skin Rash
This medicine may cause fatal skin allergies without any warnings in some patients. Signs and symptoms such as rashes, hives, fever, or other allergic symptoms should be reported to the doctor without any delay. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition.
Renal Dysfunction
This medicine should be used with caution in patients with a history of kidney diseases due to the increased risk of severe adverse effects. Close monitoring of the renal function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Hepatotoxicity
This medicine should be used with caution in patients with a history of liver diseases due to the increased risk of severe adverse effects. Close monitoring of the liver function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Thrombosis
This medicine should be used with caution in patients with a history of stroke and myocardial infarction due to the increased risk of worsening of the existing condition. Close monitoring of heart function is recommended for such patients. Report any symptoms such as a chest pain, shallow breathing, speech slurring, weakness, etc. to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
Take this medicine exactly as instructed by the doctor. Do not take larger or smaller amounts than prescribed. Seek emergency medical treatment in case of any severe side effects. Ensure that the course of treatment is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous
How it works
This medicine works by blocking the formation of certain chemical substances in the body which cause pain and swelling.
Legal Status
Classification
Category
Non-steroidal anti-inflammatory agents
Schedule
Schedule H
DailyMed - Oxaprozin tablet [Internet]. Dailymed.nlm.nih.gov. 2018 [cited 12 January 2018]. Available from:
Oxaprozin: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2018 [cited 12 January 2018]. Available from:
Oxaprozin - DrugBank [Internet]. Drugbank.ca. 2018 [cited 12 January 2018]. Available from:
[Internet]. Accessdata.fda.gov. 2018 [cited 12 January 2018]. Available from:
Information on this page was last updated on 12 Feb 2018
Disclaimer
We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.