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Ostigard (100/50 mg) Capsule

Manufactured byZydus Cadila
ContainsCelecoxib (100 mg) + Diacerein (50 mg)
Description

Ostigard (100/50 mg) Capsule is a combination medicine used in the treatment of osteoarthritis of the knee or hip joints.

Side effects

Major & minor side effects for Ostigard (100/50 mg) Capsule

  • Fever
  • Swelling of feet or lower legs
  • Increase in blood pressure
  • Diarrhea
  • Stomach pain
  • Headache
  • Heartburn
  • Runny Nose
  • Flatulence
  • Decreased appetite
  • Yellowing of skin and eyes
  • Intense yellow urine

Uses of Ostigard (100/50 mg) Capsule

What is it prescribed for?

  • Osteoarthritis
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for this medicine to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit forming tendency has been reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women. Your doctor may prescribe a safer alternative based on the clinical condition.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women. Your doctor may prescribe a safer alternative based on the clinical condition.

Allergy

This medicine is not recommended for use in patients with a known allergy to celecoxib, any other NSAIDs, diacerein, or any other anthraquinones.

Coronary Artery Bypass Surgery (CABG)

This medicine is not recommended for use before or after a coronary artery bypass graft surgery due to the increased risk of severe adverse reactions.

Severe kidney impairment

This medicine is not recommended for use in patients having a severe impairment of kidney function due to the increased risk of serious adverse effects.

Severe liver impairment

This medicine is not recommended for use in patients with a known history of severe liver impairment due to the increased risk of serious adverse effects.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women. Your doctor may prescribe a safer alternative based on the clinical condition.

Breast-feeding

This medicine is not recommended for use in breastfeeding women. Your doctor may prescribe a safer alternative based on the clinical condition.
General warnings

Heart diseases

This medicine may cause a heart attack, stroke, or other associated symptoms after a prolonged use. This risk is especially higher in patients with a history of heart diseases. Close monitoring of heart function is recommended for such patients. Report any symptoms such as a chest pain, shallow breathing, speech slurring, weakness, etc. to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Gastro-intestinal bleeding

This medicine should be used with extreme caution due to the increased risk of severe gastrointestinal bleeding, especially with prolonged use. This risk is significantly higher in the elderly population and in patients with a history of gastrointestinal diseases. Report any unusual symptoms such as blood in the stool or vomit to the doctor immediately. Replacement with a suitable alternative may be required based on the clinical condition.

Diarrhea

Use of this medicine may cause diarrhea or loose stools in the first few days of treatment. Contact your doctor if the complication is not resolved within 3-4 days.

Antibiotic therapy

This medicine should not be taken with antibiotics since the risk of gastric irritation and persistent diarrhea is significantly high in such cases. Your doctor may make appropriate changes to your therapy based on your clinical condition.

Diagnostic tests

It is recommended to monitor liver function, kidney function, complete blood count, and urine tests every six months while taking this medicine.

Intense yellowing of urine

Use of this medicine may cause intense yellow coloration of the urine. This is mainly due to the excretion of end products and may not be indicative of any complication.

Missed Dose

If a dose of this medicine is missed, take the dose as soon as you remember it. If it is almost time for the next dose, skip the missed dose and take the next dose. Do not double the dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Aluminium Hydroxide/Magnesium Hydroxide

Corticosteroids

Adefovir

Antihypertensives

Amoxycillin

Laxatives

Disease interactions

Asthma

This medicine is not recommended for use in patients with a known history of NSAID-sensitive asthma. Replacement with a suitable alternative should be done under your doctor's supervision.

Fluid Retention and edema

This medicine may cause fluid retention and edema in some patients. Close monitoring of blood pressure, electrolyte levels, and heart function may be required based on the clinical condition. Appropriate dose adjustments or replacement with a suitable alternative may be necessary in some cases.

Irritable bowel syndrome

This medicine should be used with caution in patients having an irritable bowel or other associated conditions of the gastrointestinal tract due to an increase in the risk of adverse effects. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
Food interactions
A diet rich in dietary fibers and phytates may interfere with the absorption of this medicine. Hence, administration of this medicine with a diet rich in fibers and phytates should be avoided. Your doctor/dietitian may suggest appropriate changes in your diet based on your clinical condition.
Lab interactions
Information not available.
Take this medicine exactly as prescribed by the doctor. Do not take in larger or smaller quantities than recommended. Consult the doctor if you experience any undesirable side effects. Contact your doctor if you experience prolonged diarrhea in the initial phase of treatment. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

To be taken immediately after food

To be taken as instructed by doctor

May cause sleepiness

How it works
Celecoxib works by reducing the formation of certain chemical substances in the body that cause pain and swelling. Diacerein works by blocking the actions of a certain specific protein that causes swelling, pain, and degradation of cartilage at bone joints. The combination is thus effective in the treatment of osteoarthritis.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Nonsteroidal anti-inflammatory agents, Antirheumatics

Schedule

Schedule H

[Internet]. 2017 [cited 19 September 2017]. Available from:

https://www.medicines.org.uk/emc/medicine/14534

DailyMed - Celecoxib capsule [Internet]Dailymed.nlm.nih.gov. 2017 [cited 19 September 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=27d813ea-7798-09cb-734b-b970d7248f1f

Diacerein - DrugBank [Internet]. Drugbank.ca. 2017 [cited 19 September 2017]. Available from:

https://www.drugbank.ca/drugs/DB11994

[Internet]. 2017 [cited 19 September 2017]. Available from:

http://highnoon-labs.com/wp-content/uploads/2015/04/Artrodar-Insert.pdf

Celecoxib: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 19 September 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a699022.html
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Information on this page was last updated on 29 Sep 2017

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