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Nubeta Sm (2.5/5 mg) Tablet
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Nubeta Sm (2.5/5 mg) Tablet

Manufactured byAbbott Healthcare Pvt. Ltd.
ContainsS-Amlodipine (2.5 mg) + Nebivolol (5 mg)
Description
Nubeta Sm (2.5/5 mg) Tablet is a combination of S-Amlodipine and Nebivolol. This medicine is used for the treatment of hypertension (high blood pressure). This medicine reduces heart rate that makes your heart more efficient at pumping blood throughout your body. It also decreases high blood pressure by relaxing your heart muscles. Nubeta Sm (2.5/5 mg) Tablet has some common side effects such as headache, nausea, vomiting and a sense of warmth (in your face, ears, neck and limbs). This medicine can cause swelling in your ankles. Therefore, avoid sitting for a long time and raise your legs while sitting down. Nubeta Sm (2.5/5 mg) Tablet may also cause dizziness, therefore you are recommended to avoid driving vehicles and operating machines. Rise slowly from sitting or lying position if you feel dizzy while on Nubeta Sm (2.5/5 mg) Tablet treatment. If any of these side effects do not resolve with time or get worse, seek your doctor's consultation at the earliest. Avoid taking this medicine if you are allergic to it. Nubeta Sm (2.5/5 mg) Tablet should be taken with or without food, preferably at the same time each day. Do not stop taking this medicine suddenly as it can cause your blood pressure to rise suddenly, thereby increasing the risk of heart attack and stroke. To make sure Nubeta Sm (2.5/5 mg) Tablet is safe for you, share your entire medical and medication history with your doctor. Inform your doctor if you are pregnant, planning a pregnancy or are breastfeeding.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Nubeta Sm (2.5/5 mg) Tablet

  • Difficulty in breathing
  • Dizziness
  • Irregular heartbeat
  • Chest tightness
  • Black or tarry stools
  • Blurred vision
  • Diarrhoea
  • Acid or sour stomach
  • Heartburn
  • Indigestion
  • Anxiety
  • Back pain
  • Trouble sleeping
  • Headache
  • Unusual tiredness and weakness
  • Increase in body fat and cholesterol
  • Swelling of face, lips, eyelids, tongue, hands and feet
  • Dizziness

Uses of Nubeta Sm (2.5/5 mg) Tablet

What is it prescribed for?

  • Hypertension
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    Nubeta Sm (2.5/5 mg) Tablet starts showing its action within 2 hours. However, you may start feeling well in few hours.
  • How long do the effects of this medicine last?
    This effect of Nubeta Sm (2.5/5 mg) Tablet lasts for an average duration of 24 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with Nubeta Sm (2.5/5 mg) Tablet due to the increased risk of side effects such as dizziness, lightheadedness, irregular heart rate, and fainting. It is advised that you do not perform any activities that require high mental alertness such as driving vehicles or operating machines if you consume alcohol during treatment with this medicine.
  • Is this a habit forming medicine?
    Nubeta Sm (2.5/5 mg) Tablet has no habit forming tendency.
  • Can this medicine be taken during pregnancy?
    Nubeta Sm (2.5/5 mg) Tablet is not recommended for use in pregnant women except in emergency conditions. Your doctor will weigh the benefits and any potential risks before prescribing this medicine to you.
  • Can this medicine be taken while breast-feeding?
    Nubeta Sm (2.5/5 mg) Tablet is unsafe to use in breastfeeding women. This medicine may affect the heart function of your infant. Your doctor may advise you to discontinue breastfeeding or to discontinue the medicine based on your clinical condition.

Allergy

Avoid taking Nubeta Sm (2.5/5 mg) Tablet if you are allergic to any of the medicine in this combination or any other inactive ingredients present in this tablet. Seek medical attention if you see symptoms such as skin rash, swelling (face, lips, tongue, etc.), breathing difficulty, etc.

Liver disease

Nubeta Sm (2.5/5 mg) Tablet is not recommended in severe liver impairment as it gets accumulated in the liver and affects its functioning.

Heart diseases

Nubeta Sm (2.5/5 mg) Tablet is not recommended for use with heart diseases such as: 1. Heart block (a condition where the heart beats more slowly or with an abnormal rhythm when the electrical signal that controls your heartbeat is partially or completely blocked) 2. Sinus bradycardia (Sinus bradycardia is a heart rate between 50 to 60 beats per minute at rest). 3. Heart failure (a condition in which the heart is not able to pump enough blood to meet your body's demand for blood and oxygen). 4. Cardiogenic shock (a condition in which suddenly stops pumping enough oxygen-rich blood). 5. Sick sinus syndrome (it is the name for several conditions of your heart in which the sinus node in your heart doesn't work in a proper way to create a heartbeat).

Kidney disease

Nubeta Sm (2.5/5 mg) Tablet is not recommended in the presence of kidney disease as it can increase the risk of azotemia (an elevation of blood urea nitrogen (BUN) and serum creatinine levels). Taking Nubeta Sm (2.5/5 mg) Tablet in severe kidney impaired patients (Crcl < 30 ml/min) is also not recommended as this medicine may accumulate in the kidneys and worsens the compromised kidneys.
Warnings for special population

Pregnancy

Nubeta Sm (2.5/5 mg) Tablet is not recommended for use in pregnant women except in emergency conditions. Your doctor will weigh the benefits and any potential risks before prescribing this medicine to you.

Breast-feeding

Nubeta Sm (2.5/5 mg) Tablet is unsafe to use in breastfeeding women. This medicine may affect the heart function of your infant. Your doctor may advise you to discontinue breastfeeding or to discontinue the medicine based on your clinical condition.
General warnings

Hypotension

Symptomatic hypotension (low blood pressure) may occur if there is volume depletion (excess loss of salt and fluid leading to reduced fluid volume) or those treated with high-dose diuretics (medication that increases the removal of water and salt from the body via urine). Correct this condition before initiating treatment with Nubeta Sm (2.5/5 mg) Tablet.

Driving or operating machinery

Nubeta Sm (2.5/5 mg) Tablet may cause symptoms such as drowsiness, blurred vision, or dizziness. Avoid performing any activities that require high mental alertness like driving vehicles or operating machines during treatment with this medicine if you experience any of these symptoms.

Peripheral vascular diseases

Nubeta Sm (2.5/5 mg) Tablet may aggravate symptoms of arterial insufficiency (decreased blood flow or lack of blood flow through your arteries) if there is peripheral vascular disease. Peripheral vascular disease is the reduced circulation of blood to a body part other than your brain or heart caused by a narrowed or blocked blood vessel.

Other medicines

Nubeta Sm (2.5/5 mg) Tablet may interact with many other medicines and may cause side effects. It is advised that you report to your doctor all your current medicines before beginning treatment with this medicine.

Major surgery

Nubeta Sm (2.5/5 mg) Tablet should be stopped few days before undergoing major surgery due to the increased risk of side effects.

Use in children

Nubeta Sm (2.5/5 mg) Tablet is not recommended for use in children and adolescents below the age of 18 years since the safety and efficacy of use are not clinically established.

Missed Dose

If you missed a dose of Nubeta Sm (2.5/5 mg) Tablet, take it as soon as you remember. If it's time for the next dose, skip the missed dose. Take your next dose at your usual time. Do not double the dose.

Overdose

Never take Nubeta Sm (2.5/5 mg) Tablet more than the prescribed dose. If you suspect that you might have taken an overdose of this medicine, go to the emergency department of your local hospital.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with Nubeta Sm (2.5/5 mg) Tablet due to the increased risk of side effects such as dizziness, lightheadedness, irregular heart rate, and fainting. It is advised that you do not perform any activities that require high mental alertness such as driving vehicles or operating machines if you consume alcohol during treatment with this medicine.
Interaction with Medicine

Diltiazem

Fluoxetine

Itraconazole

Amiodarone

Rifampicin

Aminophylline

Disease interactions

Asthma

Nubeta Sm (2.5/5 mg) Tablet should be used with caution if you have asthma as this medicine may worsen the condition.

Diabetes

Nubeta Sm (2.5/5 mg) Tablet should be used with caution you have Diabetes mellitus due to the increased risk of altered blood glucose levels.

Glaucoma

Nubeta Sm (2.5/5 mg) Tablet should be used with caution if you have glaucoma (angle-closer glaucoma). Symptoms include acute onset of decreased visual acuity or ocular pain and typically occur within hours to weeks of drug initiation.

Hyperlipidemia

Nubeta Sm (2.5/5 mg) Tablet should be used with caution if you have hyperlipidemia (high levels of fat in the blood). It may increase cholesterol and triglyceride levels.

Hyperthyroidism

Nubeta Sm (2.5/5 mg) Tablet should be used with caution if you have hyperthyroidism as it may mask the symptoms of hypothyroidism like tachycardia (increased heartbeat). Moreover, the abrupt withdrawal of Nubeta Sm (2.5/5 mg) Tablet may aggravate the symptoms of this condition.

Pheochromocytoma

Nubeta Sm (2.5/5 mg) Tablet should be used with caution if you have known or suspected pheochromocytoma (tumour of the adrenal gland).
Food interactions
Consumption of grapefruit juice is not recommended during treatment with Nubeta Sm (2.5/5 mg) Tablet due to the increased risk of hypotension (low blood pressure). You may experience dizziness, headache, swelling of hands and feet, etc.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Nubeta Sm (2.5/5 mg) Tablet can be taken with or without food preferably at the same time every day. Do not stop taking Nubeta Sm (2.5/5 mg) Tablet suddenly as it can cause your blood pressure to rise suddenly thereby increasing the risk of heart attack and stroke. It may cause dizziness. If this happens to you, get up slowly when rising from a sitting or lying position. Do not break, crush or chew the tablet in your mouth.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
Nubeta Sm (2.5/5 mg) Tablet is a combination of S-Amlodipine and Nebivolol. S-Amlodipine relaxes your heart muscles and blood vessels. Nebivolol relaxes your blood vessels and reduces the heart rate, promoting a smooth flow of blood. Their combination is thus effective in reducing blood pressure.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Cardioselective beta blockers, Calcium channel blocking agents, Antihypertensive combinations

Schedule

Schedule H

Medicines.org.uk. 2021. Nebivolol 5 mg Tablets - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 26 August 2021].

https://www.medicines.org.uk/emc/product/11317#PHARMACOKINETIC_PROPS>

Accessdata.fda.gov. 2021. [online] Available at: < [Accessed 26 August 2021].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/021742s013lbl.pdf>

Medicines.org.uk. 2021. Amlodipine 5mg Tablets - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 26 August 2021].

https://www.medicines.org.uk/emc/product/3478/smpc#PRODUCTINFO>

Accessdata.fda.gov. 2021. [online] Available at: < [Accessed 26 August 2021].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2007/019787s042lbl.pdf>
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Information on this page was last updated on 31 Aug 2021

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