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Nimular Sp 100/10 MG Capsule
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Nimular Sp 100/10 MG Capsule

Manufactured byStanford Laboratories
ContainsNimesulide
Description
Nimular Sp 100/10 MG Capsule is a painkiller medicine. This medicine is used in the treatment of pain. It provides relief from mild to moderate pain due to menstrual cramps and osteoarthritis (occurs when flexible tissue at the ends of your bones wears down). Nimular Sp 100/10 MG Capsule decreases the intensity of pain signals to the brain and also prevents the release of substances called prostaglandins in the brain that cause pain and fever. Nimular Sp 100/10 MG Capsule has some side effects like nausea, vomiting, heartburn, stomach pain, loss of appetite, skin rash, pain at the site of injection and diarrhoea. Consult your doctor if these side effects persist. Do not use this medicine if you are allergic to it. Nimular Sp 100/10 MG Capsule is not recommended for use in children below 12 years of age as safety is not established. Nimular Sp 100/10 MG Capsule is available in different dosage forms like tablet, tablet ER, syrup, capsule, tablet DT, tablet MD, injection, oral drops, suspension and gel. Your doctor will decide an appropriate dosage form and dose of the medicine based on your condition. Nimesulide injectables will be given by your doctor in the hospital setting. Nimular Sp 100/10 MG Capsule relieves pain and swelling due to arthritic conditions but does not cure it. Nimular Sp 100/10 MG Capsule should not be used for a long time due to the risk of severe liver damage. Maintain caution while taking this medicine if you have any kidney problems. This medicine is not recommended to be used in pregnancy and breastfeeding. Nimular Sp 100/10 MG Capsule may sometimes cause dizziness. Avoid driving vehicles or operating machines after taking this medicine. Do not consume alcohol while using this medicine as it may worsen drowsiness.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Nimular Sp 100/10 MG Capsule

  • Acid or sour stomach
  • Stomach discomfort and cramps
  • Dizziness
  • Skin rash
  • Nausea and vomiting
  • Pain at the injection site
  • Nervousness
  • Loss of appetite

Uses of Nimular Sp 100/10 MG Capsule

What is it prescribed for?

  • Pain due to osteoarthritis
  • Fever
  • Primary dysmenorrhea
  • Musculoskeletal pain
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The time of the onset of action of Nimular Sp 100/10 MG Capsule may vary based on the dosage form. Parenteral form (injection): within 15 minutes of its intravenous administration. Oral form (tablet, tablet MD, capsule, tablet ER, syrup, oral drops, suspension): it takes 2-3 hours for showing its action. Topical form (gel): unknown
  • How long do the effects of this medicine last?
    The duration of action for Nimular Sp 100/10 MG Capsule is not known.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended while treatment with Nimular Sp 100/10 MG Capsule due to the risk of stomach bleeding, drowsiness, and lack of concentration.
  • Is this a habit forming medicine?
    No habit forming tendency has been reported for Nimular Sp 100/10 MG Capsule.
  • Can this medicine be taken during pregnancy?
    Nimular Sp 100/10 MG Capsule is not recommended for use in pregnancy especially during 1st trimester, as it has been reported to cause birth defects in the newborn baby. Consult your doctor before using this medicine.
  • Can this medicine be taken while breast-feeding?
    Nimular Sp 100/10 MG Capsule is not recommended for use in breastfeeding. An alternate medicine may be preferred, especially while nursing a newborn or preterm infant. Consult your doctor before using this medicine.

Allergy

Do not take/receive Nimular Sp 100/10 MG Capsule if you are allergic to it. If you notice any symptoms such as a skin rash, itching/swelling anywhere on your body, dizziness, breathing difficulty, etc., seek medical attention immediately.

Liver disease

Nimular Sp 100/10 MG Capsule is broken down and absorbed in the liver. Therefore, if you taking large amounts of this medicine, can damage your liver. The use of this medicine is not recommended if you have severe liver problems because it can further damage your liver.

Severe kidney disease

A long term use with higher doses of some painkillers may harm normal kidney function. Nimular Sp 100/10 MG Capsule is not recommended for use if you have severe kidney problems as it can cause serious side effects.
Warnings for special population

Pregnancy

Nimular Sp 100/10 MG Capsule is not recommended for use in pregnancy especially during 1st trimester, as it has been reported to cause birth defects in the newborn baby. Consult your doctor before using this medicine.

Breast-feeding

Nimular Sp 100/10 MG Capsule is not recommended for use in breastfeeding. An alternate medicine may be preferred, especially while nursing a newborn or preterm infant. Consult your doctor before using this medicine.
General warnings

Gastro-intestinal bleeding

Long term use of Nimular Sp 100/10 MG Capsule can cause damage to the stomach and intestine. Serious conditions like bleeding, ulceration, and perforation of the stomach or intestinal wall can occur. Any symptom indicating ulceration and bleeding like chronic indigestion, the appearance of coffee coloured dry blood in stools or vomiting of blood should be reported to your doctor immediately.

Heart disease

Long-term use of Nimular Sp 100/10 MG Capsule may increase the risk of a heart attack if you have pre-existing heart conditions or heart failure. It is not used for treating pain after coronary bypass surgery.

External use only

Nimesulide gel is recommended for external use only. Avoid contact with the eyes, mucous membranes, or open wounds.

Use in Elderly

Nimular Sp 100/10 MG Capsule should be used with caution in the elderly population due to an increase in the risk of undesired side effects. Monitoring of kidney, liver and heart function and also symptoms of bleeding is necessary while receiving this medicine.

Driving or Operating machinery

Nimular Sp 100/10 MG Capsule may cause dizziness or blurred vision. Do not perform any activity such as driving a vehicle or operating a machine after taking this medicine

Use in children

The oral form of nimesulide is not recommended for use in children below 12 years of age as the safety and efficacy data is not available. Nimesulide injection is not recommended to be used in children below 18 years of age.

Other conditions

Nimesulide gel should be used with caution in conditions such as open wounds or skin with blisters as this medicine may delay the healing and instead may increase the pain.

Photosensitivity

Application of Nimesulide gel to the inflamed skin can make it photosensitive to direct sunlight and other light sources. Avoid exposing the applied area to direct sunlight.

Missed Dose

Oral forms: Take the missed dose of Nimular Sp 100/10 MG Capsule as soon as you remember. If it is almost time for the next dose, skip the missed dose. Do not double the dose to make up for the missed one. Injectable forms: It is important to take your nimesulide injection at the scheduled time. If you missed taking the dose, inform your doctor, and get an appointment for further instructions. Topical forms: Apply the missed dose of nimesulide as soon as you remember. Do not apply in more quantities to compensate for the missed dose.

Overdose

Oral forms: Never take more than the prescribed dose. Seek emergency medical treatment or contact your doctor in case you suspect an overdose of Nimular Sp 100/10 MG Capsule. Injectable form: Nimesulide injection is administered in a hospital setting by your doctor, so the likelihood of an overdose is rare. Contact your doctor if an overdose with Nimular Sp 100/10 MG Capsule is suspected. Topical forms: An overdose of nimesulide is not likely to cause severe symptoms unless it is applied for a long duration and in large amounts. However, swallowing this medicine may cause harm and immediate medical intervention may be required.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended while treatment with Nimular Sp 100/10 MG Capsule due to the risk of stomach bleeding, drowsiness, and lack of concentration.
Interaction with Medicine

Ketoconazole

Methotrexate

Warfarin

Amoxicillin and Clavulanic Acid

Disease interactions

Liver disease

Nimular Sp 100/10 MG Capsule has to be used with caution if you have liver problems. Please consult your doctor before taking the medicine. You will also be advised to undergo liver function tests (LFT) while you are on treatment with Nimular Sp 100/10 MG Capsule.

Kidney diseases

The higher doses of some painkillers may harm normal kidney function. Hence maintain caution while taking Nimular Sp 100/10 MG Capsule if you have any kidney problems.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Nimular Sp 100/10 MG Capsule is used to relieve fever and pain. Oral form: Take Nimular Sp 100/10 MG Capsule with food as advised by your doctor. Ensure that the treatment course is completed. This medicine should not be used for more than 15 days at a time. Consult your doctor if you notice any undesirable effects after taking this medicine. Parenteral form: It should be administered by a qualified healthcare professional in a clinical or hospital setting. Do not self administer. Your doctor will determine an appropriate dose of this injection based on your clinical condition. Report any undesirable side effects to your doctor promptly. Topical form: Nimesulide gel is meant for external use only. Apply the gel to the affected areas of the skin as instructed by your doctor. Avoid physical activity after application of the gel and let it rest on the affected area for few minutes. Inform your doctor if you have liver, kidney or heart problems. Nimular Sp 100/10 MG Capsule is not recommended for use if you are pregnant or are breastfeeding a woman.
Miscelleneous

To be taken with food

To be taken as instructed by doctor

May cause sleepiness

How it works
Nimular Sp 100/10 MG Capsule decreases the severity of pain signals to the brain. It also stops the release of chemicals called prostaglandins, that increase pain, and body temperature. Thus, this medicine provides relief from pain and fever and makes you feel better.
Legal Status

Approved

Banned

Unknown

Banned

Classification

Category

Nonsteroidal anti-inflammatory agents

Schedule

Schedule H

Ema.europa.eu. 2021. [online] Available at: < [Accessed 9 February 2021].

http://www.ema.europa.eu/docs/en_GB/document_library/Referrals_document/Nimesulide_107/WC500089307.pdf>

European Medicines Agency. 2021. Nimesulide - European Medicines Agency. [online] Available at: < [Accessed 9 February 2021].

http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/human/referrals/Nimesulide/human_referral_000275.jsp&mid=WC0b01ac0580024e9a>

Pubchem.ncbi.nlm.nih.gov. 2021. Nimesulide. [online] Available at: < [Accessed 9 February 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/4495>

Accessdata.fda.gov. 2021. [online] Available at: < [Accessed 9 February 2021].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/018533s040lbl.pdf>
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Information on this page was last updated on 9 Nov 2021

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