Loading interface...

Mygraft 500 mg Capsule

Manufactured byClaris Lifesciences Ltd.
Description
Mygraft 500 mg Capsule is a potent immunosuppressive agent. It is used along with other medicines to prevent the body from rejecting an organ (kidney, heart, or liver) transplant.

Side effects

Major & minor side effects for Mygraft 500 mg Capsule

  • Constipation
  • Stomach pain or swelling
  • Nausea and Vomiting
  • Trouble with sleeping
  • Pain in the arms, legs and the back
  • Uncontrolled shaking of arms or legs
  • Headache
  • Swelling of face, lips, eyelids, tongue, hands and feet
  • Severe difficulty in breathing
  • Chest pain
  • Dizziness and fainting
  • Black or tarry stools
  • Bloody or coffee colored vomit
  • Yellowing of skin and eyes

Uses of Mygraft 500 mg Capsule

What is it prescribed for?

  • Prevention of organ transplant rejection
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for this medicine to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. If the medicine is used, the infant should be monitored closely for any adverse effects.

Allergy

This medicine is not recommended for use in patients with a known allergy to mycophenolate mofetil, mycophenolic acid, mycophenolate sodium, or any other inactive ingredients present in the formulation.

Pregnancy

This medicine is not recommended for use in pregnant women since the risk of miscarriage or birth defects is significantly high. Contact your doctor immediately if you suspect pregnancy while taking this medicine. Appropriate means of birth control should be adopted while taking this medicine.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. If the medicine is used, the infant should be monitored closely for any adverse effects.
General warnings

Women of childbearing age

Women of childbearing age should take appropriate precautionary measures to avoid a pregnancy while taking this medicine. These patients are also advised to undergo a serum/urine pregnancy test prior to beginning therapy with this medicine.

Live vaccine

Vaccination with live and attenuated strains of microorganisms should be avoided while taking this medicine since the risk of severe infections is significantly high.

Skin cancer

Patients should avoid direct exposure to sunlight or sunlamps while taking this medicine due to the increased risk of skin cancer. Appropriate precautionary measures such as protective clothing, sunglasses, and sunscreen should be taken while stepping out.

Infections

The use of this medicine suppresses the immune system of patients and increases the risk of infections and sepsis. Patients should report any symptoms of an infection such as a fever or chills to the doctor immediately.

Blood cell count

Use of this medicine may affect the count of blood cells and cause associated complications. It should be used with extreme caution in patients having blood cell disorders such as anemia, neutropenia, etc. Symptoms like fever, chills, diarrhea, unexpected bruising and bleeding should be reported to the doctor on priority. Close monitoring of complete blood cell count may be necessary based on the clinical condition of the patient.

Gastrointestinal disturbances

Use of this medicine may cause ulcers and bleed in the gastrointestinal tract. This risk is especially higher in patients with a previous history of gastrointestinal diseases. It is advised that you should inform the doctor about all your medical conditions before receiving this medicine.

Other medicines

Report the use of all medicines including vaccinations, herbs, and supplements to the doctor before receiving this medicine to rule out chances of a possible interaction.

Missed Dose

Take the missed dose as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Contact your doctor if an overdose of this medicine is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Omeprazole

Sevelamer

Ethinyl Estradiol

Leflunomide

Amoxicillin and Clavulanic Acid

Live vaccines

Aluminium Hydroxide/Magnesium Hydroxide/Calcium carbonate

Cloxacillin

Disease interactions

Peptic ulcer disease

This medicine should be used with caution in patients suffering from peptic ulcer disease due to the increased risk of worsening of the patient's condition. Your doctor will schedule the uptake of medicines in such a way that adverse effects are minimized.

Kidney dysfunction

This medicine should be used with caution in patients suffering from kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Liver dysfunction

This medicine should be used with caution in patients suffering from liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Neutropenia

This medicine should be used with caution in patients with predisposed to neutropenia. Use of this medicine may cause severe neutropenia has occurred in people. It advises treatment should be discontinued or the dose reduced in patients who develop neutropenia. Closely monitoring of hematopoietic function and complete blood counts should be performed. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
Take this medicine exactly as prescribed by the doctor. It is strongly advised to take this medicine under the supervision of a doctor with frequent monitoring of blood cell count and status of the transplant acceptance by the immune system. Avoid inhalation or contact with the skin. Contact your doctor immediately if you develop signs or symptoms of an infection.
Miscelleneous

To be taken on an empty stomach

To be taken as instructed by doctor

Does not cause sleepiness

How it works
This medicine works by suppressing the immune system which is primarily responsible for organ rejection after a transplant has been completed.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Selective immunosuppressants

Schedule

Schedule H

[Internet]. Medicines.org.uk. 2020 [cited 7 April 2020]. Available from:

https://www.medicines.org.uk/emc/files/pil.5972.pdf

Mycophenolate mofetil - DrugBank [Internet]. Drugbank.ca. 2020 [cited 7 April 2020]. Available from:

https://www.drugbank.ca/drugs/DB00688

DailyMed - MYCOPHENOLATE MOFETIL capsuleMYCOPHENOLATE MOFETIL tablet, film coated [Internet]. Dailymed.nlm.nih.gov. 2020 [cited 7 April 2020]. Available from:

https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=b414303f-e6f3-4e22-a537-96be352b59a4

[Internet]. Gene.com. 2020 [cited 7 April 2020]. Available from:

https://www.gene.com/download/pdf/cellcept_medguide.pdf

Mycophenolate: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2020 [cited 7 April 2020]. Available from:

https://medlineplus.gov/druginfo/meds/a601081.html
Loading related questions...
Something doesn’t feel right?
Report an error

Information on this page was last updated on 8 Jun 2020

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.