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Monotrate 30 MG Tablet SR
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Monotrate 30 MG Tablet SR

Manufactured bySun Pharma Laboratories Ltd.
ContainsIsosorbide-5-Mononitrate
Description
Monotrate 30 MG Tablet SR is a medicine used to prevent and treat angina. Angina is chest pain that occurs when your heart muscle does not get a sufficient amount of oxygen-rich blood. It is caused due to narrowing of blood vessels that carries blood to the heart. This medicine works by relaxing the blood vessels, thus improving blood flow to the heart and decreasing workload of the heart. Monotrate 30 MG Tablet SR shows common side effects such as headache, flushing (redness of the face or neck), or dizziness upon standing. These side effects usually subside with time. However, if they persist or worsen, consult your doctor for further assistance. Avoid driving vehicles or operating heavy machines if you feel dizzy while taking this medicine. Monotrate 30 MG Tablet SR may be taken with or without food. Follow the instructions given by your doctor about the dose and duration of treatment. Take the medication at the same time every day for ease of remembering. Avoid the consumption of alcohol while taking the medicine due to the increased risk of side effects. Avoid discontinuing the medication without consulting your doctor, as it can worsen your condition. Monotrate 30 MG Tablet SR is not recommended if you are allergic to it. It should not be taken together with medicines used for sexual function problems (such as Sildenafil, Tadalafil, and Vardenafil), as it can cause a significant drop in blood pressure leading to unconsciousness. It is not recommended if you experience early signs of heart attack (chest pain, pain or discomfort spreading to your jaw, neck, shoulder, arm, or back, sweating, nausea, tiredness, and sudden dizziness). Monotrate 30 MG Tablet SR should be avoided if you have a heart condition causing thickening of the heart muscles, severe hypotension (low blood pressure), severe anaemia (low red blood cell count), and severely impaired blood flow to the brain. It should be used with caution if you have low blood pressure, glaucoma (an eye condition that may occur due to increased pressure inside the eyes), kidney conditions, or if you have had a head injury. Monotrate 30 MG Tablet SR should be used in pregnancy after consulting your doctor. It is unknown if the medicine passes into breastmilk. Hence, consult your doctor before taking the medicine if you are breastfeeding.
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Side effectsConcernsUsageRelated products

Substitutes

List of substitutes for Monotrate 30 MG Tablet SR

Isonorm 30 MG Tablet SR
Lupin Ltd.
Monit 30 MG Tablet SR
Intas Pharmaceuticals Ltd.
Nitrofix 30 MG Tablet SR
Micro Labs Ltd.
Solotrate 30 SR Tablet
Zydus Cadila

Side effects

Major & minor side effects for Monotrate 30 MG Tablet SR

  • Irregular heartbeat
  • Low blood pressure
  • Dizziness and fainting
  • Headache
  • Nausea or Vomiting
  • Chest pain
  • Difficulty in breathing
  • Lightheadedness
  • Hives and redness of skin
  • Burning, numbness, tingling in the arms and feet
  • Anxiety
  • Flushing

Uses of Monotrate 30 MG Tablet SR

What is it prescribed for?

  • Angina pectoris
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    Monotrate 30 MG Tablet SR starts to show its effect within one hour.
  • How long do the effects of this medicine last?
    The effect of Monotrate 30 MG Tablet SR may last for 8 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with Monotrate 30 MG Tablet SR as it may increase the risk of dizziness, lightheadedness, etc.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported for Monotrate 30 MG Tablet SR.
  • Can this medicine be taken during pregnancy?
    Monotrate 30 MG Tablet SR should be used during pregnancy only upon your doctor's recommendation. Consult your doctor to understand the potential risks and benefits before taking the medicine.
  • Can this medicine be taken while breast-feeding?
    Due to the lack of safety information, Monotrate 30 MG Tablet SR should be used while breastfeeding only after consulting your doctor.

Allergy

Avoid taking Monotrate 30 MG Tablet SR if you are allergic to it. Seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc.

Anaemia

Monotrate 30 MG Tablet SR is not recommended for use if you have severe anaemia. This medicine may increase the risk of methaemoglobinemia (a blood disorder in which too little oxygen is delivered to your cells.).

Heart Attack

Monotrate 30 MG Tablet SR is not recommended if you experience early signs of heart attack, such as chest pain, pain or discomfort spreading to your jaw, neck, shoulder, arm, or back, sweating, nausea, tiredness, and sudden dizziness.

Hypertrophic cardiomyopathy

Hypertrophic cardiomyopathy is a heart condition characterised by the thickening of heart muscles. Monotrate 30 MG Tablet SR is not recommended if you have hypertrophic cardiomyopathy as it may worsen your condition.

Cerebral insufficiency

Cerebral insufficiency refers to impaired blood flow to the brain. Monotrate 30 MG Tablet SR is not recommended if you have severe cerebral insufficiency as it may worsen your condition.

Severe hypotension

Monotrate 30 MG Tablet SR is not recommended if you have severe hypotension (low blood pressure) as it may worsen your condition.

Phosphodiesterase type 5 Inhibitors

Phosphodiesterase type 5 inhibitors are a class of medicines used to treat erectile dysfunction (inability to get or keep an erection firm enough for sexual intercourse in men). Combined use of Monotrate 30 MG Tablet SR and Phosphodiesterase type 5 inhibitors (such as Sildenafil, Tadalafil, or Vardenafil) is not recommended as it can cause a significant drop in blood pressure.
Warnings for special population

Pregnancy

Monotrate 30 MG Tablet SR should be used during pregnancy only upon your doctor's recommendation. Consult your doctor to understand the potential risks and benefits before taking the medicine.

Breast-feeding

Due to the lack of safety information, Monotrate 30 MG Tablet SR should be used while breastfeeding only after consulting your doctor.
General warnings

Driving vehicles and operating machines

Avoid driving vehicles and operating heavy machines while taking Monotrate 30 MG Tablet SR as it can cause dizziness.

Withdrawal symptoms

Avoid abrupt discontinuation of Monotrate 30 MG Tablet SR as it may aggravate anginal symptoms.

Head injury

Intracranial hypertension refers to increased pressure around the brain. Monotrate 30 MG Tablet SR is not recommended for use if you recently had a severe head injury or have intracranial hypertension. This medicine may increase the pressure within the skull and further worsen your condition.

Glaucoma

Glaucoma is a condition in which the optic nerve (the nerve connecting the eye to the brain) is damaged, usually due to high pressure within your eyeballs. Monotrate 30 MG Tablet SR should be used with caution if you have glaucoma as it may increase the pressure inside the eyes and worsen your condition.

Use in children

Monotrate 30 MG Tablet SR is not recommended for use in children less than 18 years of age as the safety and efficacy data are not clinically established.

Missed Dose

Do not miss the dose of Monotrate 30 MG Tablet SR. Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for the next scheduled dose. Do not double your dose to make up for the missed one.

Overdose

Do not take more than the recommended dose of Monotrate 30 MG Tablet SR. Contact your doctor immediately in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with Monotrate 30 MG Tablet SR as it may increase the risk of dizziness, lightheadedness, etc.
Interaction with Medicine

Amitriptyline

Riociguat

Alprazolam

Avanafil

Disease interactions

Hypotension

Monotrate 30 MG Tablet SR should be used with caution if you have hypotension (low blood pressure). Your doctor may closely monitor your blood pressure while you are taking this medicine.

Liver Disease

Monotrate 30 MG Tablet SR should be used with caution if you have liver conditions. Your doctor may recommend dose adjustments based on your clinical condition.

Kidney Disease

Monotrate 30 MG Tablet SR should be used with caution if you have a kidney condition. Your doctor may recommend dose adjustments based on your clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Monotrate 30 MG Tablet SR may be taken with or without food. Do not break, chew, or crush the tablet. Avoid taking more than the recommended dose as it may increase the risk of side effects. Take it at the same time every day for ease of remembering. Do not discontinue the medicine without consulting your doctor, as your condition may become worse. Avoid consumption of alcohol during treatment with this medicine as it may cause dizziness, lightheadedness, etc.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
Monotrate 30 MG Tablet SR works by relaxing the blood vessels, thus improving blood flow to the heart and decreasing the workload of the heart.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Antianginal agents

Schedule

Schedule H

Wsh.nhs.uk. 2022. [online] Available at: [Accessed 4 July 2022].

https://www.wsh.nhs.uk/CMS-Documents/Patient-leaflets/CardiacCare/5348-1IsosorbideMononitrate-DrugInformation.pdf

Balasubramanian, S. and Chowdhury, Y., 2022. Isosorbide. [online] Ncbi.nlm.nih.gov. Available at: [Accessed 4 July 2022].

https://www.ncbi.nlm.nih.gov/books/NBK557839/

Pdf.hres.ca. 2022. [online] Available at: [Accessed 18 August 2022].

https://pdf.hres.ca/dpd_pm/00043683.PDF

Medicines.org.uk. 2022. Isosorbide Mononitrate Tablets 40 mg - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: [Accessed 18 August 2022].

https://www.medicines.org.uk/emc/product/2699
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Information on this page was last updated on 18 Aug 2022

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