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Miprogen 100 MG Pessaries
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Miprogen 100 MG Pessaries

Manufactured byBharat Serums & Vaccines Ltd.
ContainsNatural Micronised Progesterone
Description
Miprogen 100 MG Pessaries is obtained from plant sources and has a similar action to the female hormone, progesterone. This medicine is used for the treatment of symptoms experienced due to periodic changes in sex hormone levels as a part of the menstrual cycle. It is also used for infertile women who need extra progesterone to support embryo implantation and early pregnancy while undergoing treatment in an Assisted Reproductive Technology (ART) program.
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Side effectsConcernsUsageRelated products

Side effects

Major & minor side effects for Miprogen 100 MG Pessaries

  • Vaginal discharge
  • Vaginal bleeding
  • Vaginal itching
  • Vaginal irritation
  • Rash

Uses of Miprogen 100 MG Pessaries

What is it prescribed for?

  • Premenstrual syndrome
  • Female infertility
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The time taken for this medicine to show it's effect is subject to vary from one person to another.
  • How long do the effects of this medicine last?
    The duration of action of this medicine is subject to vary from one person to another.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is recommended for use in pregnancy only if the need is clinically established. Consult your doctor before using this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. Discuss all the risks and benefits with your doctor before using this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to progesterone or any other inactive ingredients present along with the formulation.

Abnormal vaginal bleeding

This medicine is not recommended for use if you have an abnormal vaginal bleeding episode that has not been diagnosed by a doctor. Report any menstrual irregularities to the doctor immediately.

Breast cancer

This medicine is not recommended for use in patients with breast cancer or suspected breast cancer. Patients with a family history of breast cancer should be monitored closely during treatment with this medicine.

Miscarriage

This medicine is not recommended for use if the patient has had an incomplete miscarriage or missed abortion recently.

Heart and blood vessel disorder

This medicine is not recommended for use in patients having an active or historic instance of stroke or heart attack. It should not be used by patients having an active or historic clotting disorder.

Liver disease

This medicine is not recommended for use in patients with liver diseases due to the risk of adverse effects.
Warnings for special population

Pregnancy

This medicine is recommended for use in pregnancy only if the need is clinically established. Consult your doctor before using this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. Discuss all the risks and benefits with your doctor before using this medicine.
General warnings

Dizziness and drowsiness

The use of this medicine can cause dizziness, drowsiness, and impair the ability to perform tasks requiring cognition and alertness. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms. You are advised to take the medicine at recommended times to avoid any such effect.

Blood clotting disorder

The use of this medicine may cause the formation of a blood clot in the artery or a deep vein (thromboembolism) resulting in severe to fatal adverse effects. The use of this medicine should be stopped if any such condition is confirmed.

Diabetes

This medicine should be used with caution in patients with diabetes due to the risk of worsening the patient's condition. Close monitoring of blood glucose levels is necessary while receiving the medicine. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

Other medicines

This medicine may interact with many other medicines and may cause severe adverse effects. Hence, it is advised that you inform the doctor about all your current medicines including any herbs and supplements before beginning treatment with this medicine.

Bone mineral density

The use of this medicine may induce bone loss and may increase the risk of fractures. This risk is especially higher in patients with a known history of osteoporosis. Close monitoring of the clinical condition, appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition.

Cardiovascular disorders

The use of this medicine may increase the risk of cardiovascular diseases. Hence, this medicine should be used with caution and cardiac function monitoring is required while on this medication. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition.

Vaginal or rectal insertion

This medicine is intended for use by vaginal or rectal insertion. It is advised to use it vaginally in patients suffering from colitis or fecal incontinence and rectally in patients suffering from vaginal infections or recurrent cystitis or have recently given birth.

Missed Dose

Use the missed dose as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

Seek emergency medical attention or contact your doctor if an overdose with this medicine is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Carbamazepine

Ketoconazole

Insulin

Phenobarbital

Venetoclax

Edoxaban

Fluconazole

Disease interactions

Breast cancer

This medicine is not recommended for use in patients with a known or suspected breast cancer due to the increased risk of worsening of the patient's condition. Patients with a strong family history of breast cancer should be monitored closely during treatment with this medicine.

Thromboembolism

This medicine is not recommended for use in patients having a clotting disorder, cerebrovascular disease, or active thrombophlebitis due to the increased risk of worsening of the patient's condition. Replacement with a suitable alternative may be necessary based on the clinical condition.

Depression

This medicine should be used with caution in patients with a history of depression or active depression due to the increased risk of worsening of the patient's symptoms. Close monitoring of the clinical condition, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition.

Retinal thrombosis

The use of this medicine may sometimes cause side effects such as loss of vision, blurred vision, or retinal vascular lesions. This risk is especially higher in patients with a history of vision problems or active vision problems. Any vision problems should be reported to the doctor on priority. Close monitoring of the clinical condition, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition.

Fluid Retention and edema

This medicine should be administered cautiously in patients with fluid overload or edema due to the increased risk of worsening of the patient's condition. Close monitoring of the clinical condition, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition.

Hyperlipidemia

This medicine should be used with extreme caution in patients with hyperlipidemia (increased fat levels in the blood) due to the risk of worsening of the patient's condition. Close monitoring of lipid levels is necessary while receiving the medicine. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.
Food interactions
Information not available.
Lab interactions

Blood coagulation tests

Report the use of this medicine to the doctor before undergoing a test to measure the coagulation time. The use of this medicine may interfere with the test results.

Thyroid function tests

Report the use of this medicine if a thyroid function test is advised. This medicine may interfere with the test results.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Follow all the usage instructions mentioned on the label or the package insert. Do not use in larger or smaller quantities than recommended. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine acts by replacing the deficient corpus luteum hormone (progesterone) and creates an environment that allows a fertilized egg to implant in the endometrial membrane. This helps you to become and to stay pregnant when you are treated for infertility.
Legal Status

Approved

Unknown

Unknown

Approved

Classification

Category

Progestins

Schedule

Schedule H

Progesterone - DrugBank [Internet]. Drugbank.ca. 2020 [cited 7 February 2020]. Available from:

https://www.drugbank.ca/drugs/DB00396

Progesterone [Internet]. Pubchem.ncbi.nlm.nih.gov. 2020 [cited 7 February 2020]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/Progesterone

[Internet]. Medicines.org.uk. 2020 [cited 25 February 2020]. Available from:

https://www.medicines.org.uk/emc/files/pil.5568.pdf

[Internet]. Medicines.org.uk. 2020 [cited 25 February 2020]. Available from:

https://www.medicines.org.uk/emc/files/pil.5569.pdf
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Information on this page was last updated on 25 Feb 2020

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