Lumefantrine
Description
Lumefantrine is an anti-malarial agent used along with artemether for the treatment of an acute, uncomplicated malaria caused by Plasmodium falciparum. This medicine is not recommended for use in patients with a severe or complicated malaria.
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Side effects
Major & minor side effects for Lumefantrine
- Abdominal pain
- Vomiting
- Constipation
- Diarrhea
- Nausea
- Itching
- Rash
- Hives
Uses of Lumefantrine
What is it prescribed for?
- Acute uncomplicated malaria
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Concerns
Commonly asked questions
- Onset of actionThe amount of time required for this medicine to show its action is not clinically established.
- Duration of effectThe amount of time for which this medicine remains active in the body is not clinically established.
- Safe with alcohol?Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
- Is it habit forming?No habit-forming tendencies were reported.
- Usage in pregnancy?This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
- Usage while breast-feeding?This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.
Allergy
This medicine is not recommended for use in patients with a known allergy to lumefantrine or any other inactive ingredients present along with it.
Warnings for special population
Pregnancy
This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
Breast-feeding
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.
General warnings
QT Prolongation
This medicine should be used with extreme caution in patients suffering from QT prolongation due to the increased risk of worsening of the patient condition. Close monitoring of heart function and vital signs, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition.
Liver impairment
This medicine should be used with caution in patients with liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.
Kidney impairment
This medicine should be used with caution in patients with kidney diseases due to the increased risk of severe adverse effects. Close monitoring of renal function is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.
Missed Dose
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.
Overdose
Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol
Description
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Instructions
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine
Doxorubicin
Doxepin
Azithromycin
Citalopram
Duloxetine
Disease interactions
Disease
Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
Take this medicine with food, as directed by your doctor. Do not take in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous
How it works
This medicine works by interfering with the formation of certain vital substances in the cell of the malarial parasite. This leads to the eventual death of the malaria parasite.
Legal Status
Classification
Category
Antimalarial agents
Schedule
Schedule H
Lumefantrine - DrugBank [Internet]. Drugbank.ca. 2018 [cited 10 April 2018]. Available from:
Lumefantrine [Internet]. Pubchem.ncbi.nlm.nih.gov. 2018 [cited 10 April 2018]. Available from:
[Internet]. Pharma.us.novartis.com. 2018 [cited 10 April 2018]. Available from:
[Internet]. Davisplus.fadavis.com. 2018 [cited 10 April 2018]. Available from:
Information on this page was last updated on 18 Apr 2018
Disclaimer
We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.