Ledipasvir
Description
Ledipasvir is an antiviral medicine used in combination with other medicines for the treatment of chronic hepatitis C infection, genotype 1. This medicine should be used with extreme caution in patients with a known history of hepatitis B infection due to the increased risk of serious adverse reactions.
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Side effects
Major & minor side effects for Ledipasvir
- Blurred vision
- Nausea
- Vomiting
- Diarrhea
- Abdominal pain
- Itching
- Rash
- Dry skin
- Difficulty in falling asleep
- Irritability
- Chest pain
- Fever
Uses of Ledipasvir
What is it prescribed for?
- Chronic Hepatitis C
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Concerns
Commonly asked questions
- Onset of actionThe amount of time required for this medicine to show its action is not clinically established.
- Duration of effectThe amount of time for which this medicine remains active in the body is not clinically established.
- Safe with alcohol?Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
- Is it habit forming?No habit-forming tendencies were reported.
- Usage in pregnancy?This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
- Usage while breast-feeding?This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
Allergy
This medicine is not recommended for use in patients with a known allergy to ledipasvir or any other inactive ingredients present along with it.
Warnings for special population
Pregnancy
This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
Breast-feeding
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
General warnings
Liver impairment
This medicine should be used with caution in patients with a history of liver diseases due to the increased risk of serious adverse effects. Close monitoring of liver function tests is necessary for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.
Hepatitis B
This medicine should be used with extreme caution in patients with a known history of hepatitis B due to the increased risk of worsening of the patient's condition. Replacement with a suitable alternative may be necessary in some cases based on the clinical condition of the patient. Screening for hepatitis B prior to beginning treatment with this medicine is advised.
Missed Dose
The missed dose should be taken as soon as possible. It is advisable to skip the missed dose if it is already time for your next scheduled dose. Do not use extra medicine to make up for the missed dose.
Overdose
Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol
Description
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Instructions
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine
Amitriptyline
Amlodipine
Digoxin
Citalopram
Amiodarone
Disease interactions
Disease
Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
Take this medicine with or without food. Do not take in larger amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous
How it works
It works by stopping the hepatitis C virus from multiplying in the body. This helps in inhibiting the spread of the infection.
Legal Status
Classification
Category
Miscellaneous antivirals
Schedule
Schedule H
Ledipasvir - DrugBank [Internet]. Drugbank.ca. 2018 [cited 9 April 2018]. Available from:
Ledipasvir [Internet]. Pubchem.ncbi.nlm.nih.gov. 2018 [cited 9 April 2018]. Available from:
[Internet]. Accessdata.fda.gov. 2018 [cited 9 April 2018]. Available from:
[Internet]. Medicines.org.uk. 2018 [cited 9 April 2018]. Available from:
Information on this page was last updated on 11 Apr 2018
Disclaimer
We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.