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Largyl 400 MG Tablet

Manufactured byLark Laboratories Ltd.
Description
Largyl 400 MG Tablet is an antibiotic medicine that contains Metronidazole. It is used in the treatment of infections of the stomach, intestines, liver, lungs, heart, vagina, and skin. It is also used in the combination with other antibiotics in surgical prophylaxis. This medicine acts by killing the bacteria and preventing the spread of infection. Largyl 400 MG Tablet may show some common side effects such as dizziness, stomach ache, diarrhoea, metallic taste in the mouth, etc. These side effects are mild and may subside by themselves. Consult your doctor if any of these symptoms bother you for a long time or worsen. Avoid consuming alcohol as it may lead to undesired effects like nausea, vomiting, stomach discomfort, etc. Do not take this medicine if you are allergic to it. Largyl 400 MG Tablet should be taken after food. Take this medicine as prescribed by your doctor. Take it every day at the same time for the ease of remembering and for its effectiveness. Do not take more than the prescribed dose. Complete the course of treatment even if you feel better after taking a few doses. Abrupt discontinuation may make this medicine ineffective when used for future infections. If you still feel unwell after completing your antibiotic course, inform your doctor. Largyl 400 MG Tablet may not be suitable for all people. Inform your doctor if you have liver problems, low blood count, and your ongoing medications. Consult your doctor if you are pregnant or breastfeeding before taking this medicine.

Side effects

Major & minor side effects for Largyl 400 MG Tablet

  • Agitation
  • Blurred vision
  • Burning or tingling sensation of hands and feet
  • Confusion
  • Dizziness
  • Headache
  • Nasal congestion
  • Skin Rash
  • Bleeding gums
  • Constipation
  • Dark urine
  • Fast heartbeat
  • Stomach ache
  • Metallic taste

Uses of Largyl 400 MG Tablet

What is it prescribed for?

  • Bacterial infections
  • Parasitic infections
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    Largyl 400 MG Tablet may start showing its effect within 4 hours of intake.
  • How long do the effects of this medicine last?
    The duration of action for Largyl 400 MG Tablet is about 12 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Avoid consuming alcohol while taking Largyl 400 MG Tablet as it may cause symptoms like fast heartbeat, warmth, headache, and breathing difficulty.
  • Is this a habit forming medicine?
    No habit-forming tendency has been reported for Largyl 400 MG Tablet.
  • Can this medicine be taken during pregnancy?
    Largyl 400 MG Tablet is considered safe to be used in pregnancy. However, if you are pregnant, consult your doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    Largyl 400 MG Tablet is not recommended for use in breastfeeding. However, if you are breastfeeding, consult your doctor before taking this medicine. If this medicine is used, your infant should be observed for diarrhoea or diaper rash symptoms.

Allergy

Avoid taking Largyl 400 MG Tablet if you are allergic to it. Seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc.
Warnings for special population

Pregnancy

Largyl 400 MG Tablet is considered safe to be used in pregnancy. However, if you are pregnant, consult your doctor before taking this medicine.

Breast-feeding

Largyl 400 MG Tablet is not recommended for use in breastfeeding. However, if you are breastfeeding, consult your doctor before taking this medicine. If this medicine is used, your infant should be observed for diarrhoea or diaper rash symptoms.
General warnings

Blood cell count

Taking Largyl 400 MG Tablet for prolonged periods can decrease total blood cell count. Your doctor may suggest tests to monitor your blood count if necessary based on your condition.

Neurologic toxicity

Use Largyl 400 MG Tablet with caution as it may show side effects like convulsions (a sudden, irregular movement of the body, caused by involuntary contraction of muscles), peripheral neuropathy (pain due to nerve damage), headache, and dizziness.

Liver disease

Use Largyl 400 MG Tablet with caution if you have liver problems due to the increased risk of liver damage. Your doctor may suggest tests for monitoring your liver condition if necessary while on treatment with this medicine.

Dialysis

Dialysis is the procedure to remove waste products from your blood when the kidney fails to do it. The desired effect of Largyl 400 MG Tablet is not achieved if you are undergoing dialysis. Your doctor may schedule the dose for administration after the dialysis procedure or supplemental doses can be given after dialysis.

Antibiotic resistance

Finish your entire course of treatment with Largyl 400 MG Tablet, even if the condition gets better to avoid antibiotic resistance (a condition where microbes evolve mechanisms that protect them from the effects of antibiotics). If you still feel unwell after completing your antibiotic course, consult your doctor.

Driving or operating machines

Largyl 400 MG Tablet may cause dizziness, confusion, or disorientation in some people. Hence, do not perform activities that require your concentration like driving vehicles or operating machines if you experience any of these symptoms.

Missed Dose

Try not to skip any dose of Largyl 400 MG Tablet. If you forget to take a dose, take it as soon as you remember. However, if the delay is more than 12 hours, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Never take more than the prescribed dose. Seek emergency medical treatment in case of an overdose with Largyl 400 MG Tablet.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Avoid consuming alcohol while taking Largyl 400 MG Tablet as it may cause symptoms like fast heartbeat, warmth, headache, and breathing difficulty.
Interaction with Medicine

Warfarin

Ethinyl Estradiol

Atorvastatin

Disulfiram

Phenytoin

Lithium

Disease interactions

Colitis

Largyl 400 MG Tablet can kill the helpful bacteria in your stomach or intestine and leads to diarrhoea. Therefore, use Largyl 400 MG Tablet with extreme caution if you have any gastrointestinal diseases, particularly colitis (swelling of the inner lining of the colon), since it may worsen these conditions.

Neurologic toxicity

Use Largyl 400 MG Tablet with caution as it may show side effects like convulsions (a sudden, irregular movement of the body, caused by involuntary contraction of muscles), peripheral neuropathy (pain due to nerve damage), headache, and dizziness.

Liver disease

Use Largyl 400 MG Tablet with caution if you have liver problems due to the increased risk of liver damage. Your doctor may suggest tests for monitoring your liver condition if necessary while on treatment with this medicine.
Food interactions
Information not available.
Lab interactions
Information not available.
Take Largyl 400 MG Tablet with food. Do not take more or fewer than the prescribed dose. Consult your doctor if you experience any undesirable effects. Do not stop taking this medicine without consulting your doctor. Drink an adequate amount of water in order to reduce the risk of kidney injury. Keep away from the reach of children and pets. Ensure that unused medicine is disposed of properly.
Miscelleneous

To be taken with food

To be taken as instructed by doctor

May cause sleepiness

How it works
Largyl 400 MG Tablet works by interfering with the DNA formation in the bacterial cell and stopping the protein synthesis. This action kills the bacteria and prevents infection from spreading.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Amebicides, Miscellaneous antibiotics

Schedule

Schedule H

Drugs, H., 2021. Metronidazole: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 6 October 2021].

https://medlineplus.gov/druginfo/meds/a689011.html>

Medicines.org.uk. 2021. Metronidazole Tablets 500 mg - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 28 October 2021].

https://www.medicines.org.uk/emc/product/5882/smpc#gref>

Pubchem.ncbi.nlm.nih.gov. 2021. Metronidazole. [online] Available at: < [Accessed 28 October 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Metronidazole>

Dailymed.nlm.nih.gov. 2021. DailyMed - metronidazole- Metronidazole tablet. [online] Available at: < [Accessed 28 October 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a66abf44-9ae9-4342-b69a-ebaa1f9b7d78>
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Information on this page was last updated on 8 Nov 2021

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