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Indonet 75 mg Capsule SR

Manufactured byBennet Pharmaceuticals Ltd.
ContainsIndomethacin
Description
Indonet 75 mg Capsule SR is used in reducing mild to moderate pain and swelling in conditions like osteoarthritis (wearing off of the flexible tissues of your bone), rheumatoid arthritis (pain and swelling in joints), gout (deposition of crystals between your joints), and ankylosing spondylitis (fusion of small bones in your spine). Indonet 75 mg Capsule SR works by blocking the release of a specific chemical substance known as prostaglandin, responsible for pain and swelling. Indonet 75 mg Capsule SR has some side effects like stomach pain, diarrhoea, nausea, vomiting, loss of appetite, indigestion, and heartburn. However, these side effects can be prevented by taking the medication with milk or a meal. Inform your doctor if these side effects persist or worsen. Avoid taking this medicine if you have been allergic to it. Indonet 75 mg Capsule SR may cause dizziness, drowsiness or visual disturbances. Therefore, it is advisable not to drive or do anything that requires concentration. Alcohol intake is not recommended as it may result in side effects such as dizziness and stomach and/or intestinal bleeding. Inform your doctor if you have a history of ulcers or have undergone bypass surgery or have any problems related to your heart, kidneys, or liver. Inform your doctor about any other medications you are taking because they may affect or be affected by this medication. Indonet 75 mg Capsule SR is unsafe for use in pregnancy and while breastfeeding. Hence, consult your doctor if you are pregnant, planning a pregnancy, or are breastfeeding.

Side effects

Major & minor side effects for Indonet 75 mg Capsule SR

  • Acid or sour stomach
  • Diarrhoea
  • Nausea and Vomiting
  • Indigestion
  • Fever with chills
  • Skin rash
  • Dizziness
  • Headache
  • Ringing or buzzing in the ears
  • Constipation
  • Unusual tiredness and weakness
  • Visual disturbances

Uses of Indonet 75 mg Capsule SR

What is it prescribed for?

  • Osteoarthritis
  • Rheumatoid Arthritis
  • Ankylosing Spondylitis
  • Bursitis
  • Tendinitis
  • Acute Gout
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    Indonet 75 mg Capsule SR start showing its effect within 1 hour.
  • How long do the effects of this medicine last?
    The effect of Indonet 75 mg Capsule SR lasts for an average duration of 4 to 6 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended while receiving Indonet 75 mg Capsule SR due to the increased risk of gastrointestinal bleeding.
  • Is this a habit forming medicine?
    Indonet 75 mg Capsule SR has no habit forming tendency.
  • Can this medicine be taken during pregnancy?
    Indonet 75 mg Capsule SR is not advisable for pregnant women, especially in the 3rd trimester as it may affect your foetus. Your doctor may prescribe this medicine if the benefits outweigh the risk.
  • Can this medicine be taken while breast-feeding?
    Indonet 75 mg Capsule SR is known to pass into the breastmilk. It should not be used in breastfeeding women as it may affect your infant. Your doctor may advise you to discontinue breastfeeding while taking this medicine.

Allergy

It is advisable to avoid Indonet 75 mg Capsule SR if you are allergic to it. Inform your doctor if you have a known allergy to painkillers or any other proteolytic enzymes. If any symptoms occur such as skin rash, nausea, vomiting, difficulty breathing, and shock, seek an immediate medical treatment.

Peptic Ulcer

A peptic ulcer is an open sore that occurs on the inner lining of your stomach and the upper region of your small intestine. Indonet 75 mg Capsule SR is not recommended for use in patients with a peptic ulcers as this medicine acts by blocking the action of prostaglandins. Prostaglandins protect against harmful chemicals in the gastric lining. As the release of prostaglandins is blocked by this medicine there are chances of bleeding or leads to holes in your stomach or intestine and can worsen your condition. Inform your doctor if you have the history of ulcer or gastrointestinal bleeding.

Coronary Artery Bypass Surgery (CABG)

Coronary Artery Bypass Surgery is a surgical procedure that increases blood flow to your heart. Indonet 75 mg Capsule SR is not recommended for use in such patients as it increases the chances of heart attack or stroke.

Asthma

Asthma is a disorder in which the airways in your lungs constrict and swell, increasing mucus production. Indonet 75 mg Capsule SR is not recommended for use if there is a known history of NSAID-sensitive asthma. This medicine can cause narrowing of your airway and results in a breathing problem which can worsen the condition.
Warnings for special population

Pregnancy

Indonet 75 mg Capsule SR is not advisable for pregnant women, especially in the 3rd trimester as it may affect your foetus. Your doctor may prescribe this medicine if the benefits outweigh the risk.

Breast-feeding

Indonet 75 mg Capsule SR is known to pass into the breastmilk. It should not be used in breastfeeding women as it may affect your infant. Your doctor may advise you to discontinue breastfeeding while taking this medicine.
General warnings

Gastrointestinal bleeding

Indonet 75 mg Capsule SR may cause severe bleeding or a hole in the linings of your digestive tract upon prolonged usage. These adverse events may occur with or without any warning or symptoms. This risk is especially higher in the elderly population and if there is a history of gastrointestinal diseases.

Skin rash

Indonet 75 mg Capsule SR may result in skin allergy without a warning. This includes rashes, fever, and other allergy symptoms. In such cases, it is advisable to report to your doctor as soon as possible.

Hypertension

Indonet 75 mg Capsule SR should be used with caution if you have hypertension (increased blood pressure) as it may reduce the effect of anti-hypertensive medicines.

Elderly population

Indonet 75 mg Capsule SR should be used with caution in the elderly population due to an increase in the risk of undesired side effects. Your doctor may monitor your kidney function and symptoms of bleeding while you are taking this medicine.

Heart diseases

Indonet 75 mg Capsule SR should be used with caution in the presence of heart diseases due to the increased risk of side effects on your heart, especially after prolonged use. Your doctor may monitor your heart function while you are taking this medicine.

Driving or operating machinery

Use of Indonet 75 mg Capsule SR may cause drowsiness, visual disturbances, fatigue, dizziness, etc. It is advised that you do not perform any activities such as driving vehicles or operating machines if you experience any of these symptoms.

Missed Dose

If you missed a Indonet 75 mg Capsule SR dose, make sure that you remember to take your next dose on time. Do not take two doses together to make up for a forgotten dose.

Overdose

Never take more than the prescribed dose. Seek an emergency medical treatment or contact your doctor in case you suspect an overdose of Indonet 75 mg Capsule SR.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended while receiving Indonet 75 mg Capsule SR due to the increased risk of gastrointestinal bleeding.
Interaction with Medicine

Methotrexate

Warfarin

Corticosteroids

Antihypertensives

Ketorolac

Disease interactions

Fluid Retention and edema

Fluid Retention and oedema are swelling of the lower layer of skin caused by excessive fluid trapped beneath your body tissues. The use of painkillers has been associated with fluid retention and oedema. In individuals with preexisting fluid retention, hypertension (increased blood pressure), or a history of heart failure, Indonet 75 mg Capsule SR should be used with caution.

Anemia

Indonet 75 mg Capsule SR should be used with caution in case of anaemia due to the increased risk of low haemoglobin levels.

Kidney disease

Indonet 75 mg Capsule SR should be used with caution in patients with a history of any kidney disease as this medicine gets accumulated in the impaired kidneys.

Gastro-Intestinal toxicity

Gastrointestinal toxicity symptoms are nausea, vomiting, indigestion, stomach pain, etc. Indonet 75 mg Capsule SR may cause damage to your stomach, intestines, liver, etc., especially on prolonged use. Consult your doctor if there are any symptoms, such as indigestion, blood in your stool or vomit.

Liver Disease

Indonet 75 mg Capsule SR should be used with caution in case of liver disease as this medicine gets accumulated in the impaired liver.
Food interactions
Information not available.
Lab interactions
Information not available.
Take Indonet 75 mg Capsule SR with food or milk to prevent an upset stomach. Take it as per the dose and duration prescribed by your doctor. Long term use may lead to complications such as stomach bleeding and kidney problems. It may cause dizziness, drowsiness or visual disturbances. Use caution while driving or doing anything that requires concentration. Your doctor may regularly monitor your kidney function, liver function and levels of blood components if you are taking this medicine for long-term treatment. Do not open, crush or chew the capsule in your mouth.
Miscelleneous

To be taken after food

To be taken as instructed by doctor

May cause sleepiness

How it works
Indonet 75 mg Capsule SR works by reducing the formation of chemical substances known as prostaglandins in your body that causes pain and swelling.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Nonsteroidal anti-inflammatory agents

Schedule

Schedule H

Pubchem.ncbi.nlm.nih.gov. 2021. Indomethacin. [online] Available at: < [Accessed 30 August 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Indomethacin>

Accessdata.fda.gov. 2021. [online] Available at: < [Accessed 30 August 2021].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/018829s022lbl.pdf>

Medicines.org.uk. 2021. Indometacin Capsules BP 25mg - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 30 August 2021].

https://www.medicines.org.uk/emc/product/4534/smpc#PHARMACOKINETIC_PROPS>

Accessdata.fda.gov. 2021. [online] Available at: < [Accessed 30 August 2021].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2007/016059s097,017814s040,018332s030lbl.pdf>
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Information on this page was last updated on 17 Sep 2021

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