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Hibrid (125/31.25 mg) Dry Syrup

Manufactured byShreya Life Sciences Pvt. Ltd.
ContainsAmoxycillin (125 mg) + Clavulanic Acid (31.25 mg)
Description
Hibrid (125/31.25 mg) Dry Syrup is a combination of Amoxycillin and Clavulanic acid. It is used orally to treat many bacterial infections of the lungs, middle ear, sinuses, skin, teeth, and urinary tract. Amoxycillin interferes with the growth and division process of the bacterial cell wall while Clavulanic acid enhances the activity of Amoxycillin against bacteria. Hibrid (125/31.25 mg) Dry Syrup shows some side effects like nausea, vomiting, stomach pain, and skin rash. Consult your child's doctor at the earliest if any of these side effects persist or worsen. Before giving this medicine to your child, inform your doctor if your child is allergic to it. Hibrid (125/31.25 mg) Dry Syrup can be given to your child with food as it improves absorption and decreases the risks of an upset stomach. Your child's doctor will decide the dose and frequency based on the severity of the infection, your child's body weight and age. Ensure to complete the course of treatment even if your child starts feeling better. Hibrid (125/31.25 mg) Dry Syrup is generally meant to be used in children. However, your doctor may prescribe this medicine to people who cannot swallow a tablet or capsule form of this medicine. Hibrid (125/31.25 mg) Dry Syrup may interact with other medicines used. Inform your child's doctor about any health conditions like problems related to lung, stomach or intestine, liver and kidney. This information is critical as it can help your child's doctor in planning an overall treatment and dose adjustments for your child.

Side effects

Major & minor side effects for Hibrid (125/31.25 mg) Dry Syrup

  • Allergic Skin Reaction
  • Diarrhoea
  • Fever
  • Joint pain
  • Skin yellowing
  • Easy bruising and bleeding
  • Tooth discoloration
  • Nausea or vomiting
  • Altered sense of taste
  • Black or tarry stools
  • Muscle or joint pain
  • Sleeplessness
  • Irregular heartbeat

Uses of Hibrid (125/31.25 mg) Dry Syrup

What is it prescribed for?

  • Acute otitis media
  • Sinusitis
  • Lower Respiratory Tract Infection
  • Skin Infection
  • Urinary Tract Infection
  • Osteomyelitis
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    Hibrid (125/31.25 mg) Dry Syrup starts working within 1-2 hours of taking it.
  • How long do the effects of this medicine last?
    The effect of Hibrid (125/31.25 mg) Dry Syrup lasts for an average duration of 12 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    Hibrid (125/31.25 mg) Dry Syrup has no habit forming tendency.
  • Can this medicine be taken during pregnancy?
    Hibrid (125/31.25 mg) Dry Syrup is generally meant for child use.
  • Can this medicine be taken while breast-feeding?
    Hibrid (125/31.25 mg) Dry Syrup is generally meant for child use.

Allergy

Avoid Hibrid (125/31.25 mg) Dry Syrup if your child is allergic to it. Seek immediate medical attention if you notice any symptoms of allergic reactions such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulties, etc.

Cholestasis

Hibrid (125/31.25 mg) Dry Syrup should be avoided for use if your child has/had a condition where the normal flow of bile from the liver is interrupted (cholestasis).

Liver dysfunction

Avoid using Hibrid (125/31.25 mg) Dry Syrup if your child has a history of liver problems associated with the use of this medicine or any other antibiotics.
Warnings for special population

Pregnancy

Hibrid (125/31.25 mg) Dry Syrup is generally meant for child use.

Breast-feeding

Hibrid (125/31.25 mg) Dry Syrup is generally meant for child use.
General warnings

Diarrhoea

Hibrid (125/31.25 mg) Dry Syrup can cause diarrhoea because it may also kill the helpful bacteria in your stomach or intestine. Get emergency medical help if you experience severe diarrhoea that is watery or bloody.

Antibiotic resistance

Usage of Hibrid (125/31.25 mg) Dry Syrup without sufficient proof or suspicion of a bacterial infection should be avoided. Irrational dosing (overuse of antibiotics) might fail in providing the benefits and even cause toxicity. It may also increase the risk of the development of bacteria that are antibiotic-resistant.

Liver disease

Regular monitoring of the liver enzyme levels is necessary while taking Hibrid (125/31.25 mg) Dry Syrup and even after treatment with this medicine is complete.

Form of medication

Hibrid (125/31.25 mg) Dry Syrup is normally used in children. However, adults who are unable to chew or swallow the solid form of this medicine can take Hibrid (125/31.25 mg) Dry Syrup under a doctor's supervision.

Missed Dose

If you missed giving a Hibrid (125/31.25 mg) Dry Syrup dose to your child, make sure that you remember to give the next dose on time. Do not give two doses together to make up for a forgotten dose.

Overdose

Never give Hibrid (125/31.25 mg) Dry Syrup more than the prescribed dose. If you suspect that you might have given an overdose of this medicine and observing difficulty in the child, go to the emergency department of your local hospital.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Doxycycline

Methotrexate

Warfarin

Live vaccines

Disease interactions

Mononucleosis

Mononucleosis (kissing disease) may develop a maculopapular skin rash after 5-10 days of treatment with this medicine and resolves within days of discontinuing the use. Hibrid (125/31.25 mg) Dry Syrup may not be appropriate medicine in people with mononucleosis.

Colitis

Hibrid (125/31.25 mg) Dry Syrup can kill the helpful bacteria in the stomach or intestine and leads to diarrhoea. Therefore, use this medicine with extreme caution in your child if there is colitis (swelling of the inner lining of the colon).

Kidney Disease

Individuals with kidney diseases need special consideration while taking Hibrid (125/31.25 mg) Dry Syrup due to the risk of kidney damage. Dose adjustment should be done based on the clinical condition.
Food interactions
Information not available.
Lab interactions

Urine Sugar Test (Benedict's of Fehling's reagent)

High urine concentrations of Hibrid (125/31.25 mg) Dry Syrup might give a false-positive result for the urine sugar test (test to determine the presence of glucose).
Give Hibrid (125/31.25 mg) Dry Syrup orally to your child with food to decrease an upset stomach. Your child must complete the entire course of Hibrid (125/31.25 mg) Dry Syrup. Stopping the treatment early may cause the bacteria to multiply again, become resistant, or cause another infection. Your child may have a bitter taste in the mouth after the intake of Hibrid (125/31.25 mg) Dry Syrup. Eating citrus fruit or sipping plenty of water or fruit juice may help. Encourage your child to drink plenty of water in case diarrhoea develops as a side effect. Never give Hibrid (125/31.25 mg) Dry Syrup until and unless prescribed by your child's doctor. You must never share your child’s medicine with anyone else even if they show similar symptoms. Do not give Hibrid (125/31.25 mg) Dry Syrup to treat the common cold and flu-like symptoms caused by viruses. Never save medicine for future illnesses. It cannot be said whether the same medicine will work on future infections. Discard the medicine if the seal is broken or the appearance of the liquid changes. Stop Hibrid (125/31.25 mg) Dry Syrup immediately if your child develops an itchy rash, facial swelling, or breathing difficulty. Report to your doctor without any delay.
Miscelleneous

To be taken with food

To be taken as instructed by doctor

Does not cause sleepiness

How it works
Hibrid (125/31.25 mg) Dry Syrup is a combination of Amoxycillin and Clavulanic acid. Amoxycillin binds to certain specific receptors and prevents the formation of a necessary component for the cell wall building process. Clavulanic acid is effective against a specific species of bacteria that are resistant to other antibiotic medicines. Thus, the combination becomes effective against an extended range of bacteria.
Legal Status

Approved

Approved

Unknown

Approved

Classification

Category

Beta-lactamase inhibitors, Aminopenicillins

Schedule

Schedule H

Pubchem.ncbi.nlm.nih.gov. 2021. Amoxicillin. [online] Available at: < [Accessed 22 January 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Amoxicillin>

Pubchem.ncbi.nlm.nih.gov. 2021. Clavulanic acid. [online] Available at: < [Accessed 20 May 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Clavulanic-acid>

Medsafe.govt.nz. 2021. [online] Available at: < [Accessed 23 September 2021].

http://www.medsafe.govt.nz/consumers/cmi/a/AugmentinSyr.pdf>

Dailymed.nlm.nih.gov. 2021. DailyMed - AMOXICILLAN AND CLAVULANATE POTASSIUM tablet, film coated. [online] Available at: < [Accessed 20 May 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=909c85de-c076-4444-b63c-cd8bdc556f36>

Drugs, H., 2021. Amoxicillin and Clavulanic Acid: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 20 May 2021].

https://medlineplus.gov/druginfo/meds/a685024.html>
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Information on this page was last updated on 4 Oct 2021

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