Edaravone
Description
Edaravone is used in the treatment of Amyotrophic Lateral Sclerosis (ALS), a nerve disorder which weakens and shrinks the muscles due to the slow destruction of nerve cells controlling muscle movements. This medicine slows the progression of the disease and does not cure the disease or improves the muscle movements.
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Side effects
Major & minor side effects for Edaravone
- Hypersensitivity
- Easy bruising and bleeding
- Gait disturbance
- Headache
- Respiratory failure/hypoxia
- Decrease in blood cell count
- Increased liver enzyme levels
- Kidney Impairment
- Nausea and vomiting
Uses of Edaravone
What is it prescribed for?
- Amyotrophic lateral scelrosis (ALS)
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Concerns
Commonly asked questions
- Onset of actionThe amount of time required for this medicine to show its action is not clinically established.
- Duration of effectThe amount of time for which this medicine remains active in the body is not clinically established.
- Safe with alcohol?Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
- Is it habit forming?No habit forming tendencies were reported.
- Usage in pregnancy?This medicine is not recommended for use in pregnant women unless absolutely necessary. The risks and benefits should be discussed with the doctor before using this medicine.
- Usage while breast-feeding?This medicine is not recommended for use in breastfeeding women unless absolutely necessary. The risks and benefits should be discussed with the doctor before using this medicine.
Allergy
This medicine is not recommended for use in patients with a known allergy to edaravone or any other inactive ingredients present along with it.
Warnings for special population
Pregnancy
This medicine is not recommended for use in pregnant women unless absolutely necessary. The risks and benefits should be discussed with the doctor before using this medicine.
Breast-feeding
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. The risks and benefits should be discussed with the doctor before using this medicine.
General warnings
Route of administration
Edaravone should be administered as an intravenous infusion only.
Use in geriatrics
Extreme caution is advised while using Edaravone in elderly patients due to the increased risk of life-threatening adverse effects.
Use in pediatrics
This medicine is not recommended for use in children and adolescents.
Renal impairment
Edaravone should be used with extreme caution in patients with impaired kidney function due to the increased risk of kidney failure.
Missed Dose
If you miss an appointment for a dose of Edaravone, contact your doctor immediately and schedule the dose as soon as possible.
Overdose
Since this medicine is administered in the hospital setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol
Description
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Instructions
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine
Antibiotics
Disease interactions
Disease
Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
This medicine is usually administered by a qualified healthcare professional. Follow all the instructions given by your doctor and do not miss an appointment to receive this medicine. Consult your doctor if you experience any undesirable effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous
How it works
Edaravone works by slowing the destruction of nerve cells, thereby slowing the progression of the disease and worsening of the patient's condition.
Legal Status
Classification
Category
Antioxidants, Free radical scavengers
Schedule
N/A
Edaravone Injection: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 19 August 2017]. Available from:
DailyMed - RADICAVA- edaravone injection [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 19 August 2017]. Available from:
Edaravone - DrugBank [Internet]. Drugbank.ca. 2017 [cited 19 August 2017]. Available from:
[Internet]. Genome.jp. 2017 [cited 19 August 2017]. Available from:
[Internet]. 2017 [cited 19 August 2017]. Available from:
Information on this page was last updated on 29 Aug 2017
Disclaimer
We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.